“…The force microscope in its dynamic mode ͑dynamic SFM͒ offers the possibility to image surfaces with a true atomic resolution, [11][12][13] and indeed, to a greater extent in recent years, the dynamic SFM has been used for the imaging of nanoclusters on many types of surfaces. [14][15][16][17][18][19][20][21][22][23][24] However, also in dynamic SFM, the tip-surface convolution strongly reduces the resolution during imaging of the nanoclusters in the standard topography mode. 19,25,26 Furthermore, the scanning speed is limited and does not exceed speeds much higher than ϳ1 − 2 Hz, which does not permit time-dependent measurements on short time scales--a particular problem for biophysical SPM studies.…”