Learning and limbic lesions

Douglas, Ronald G.; Pribram, Karl H.

doi:10.1016/0028-3932(66)90028-5

Cited by 370 publications

(130 citation statements)

References 22 publications

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“…This idea is an extension of earlier theoretical notions that the amygdala is involved in the interpretation and integration of reinforcement (Weiskrantz, 1956), serves as a reinforcement register (Douglas & Pribram, 1966), mediates stimulus-reinforcement associations (Jones & Mishkin, 1972) and serves to associate stimuli with reward value (Gaffan, 1992). …”

Section: Short-term or Working Memory --Affect Attributementioning

confidence: 79%

Neurobiological foundations of an attribute model of memory

Kesner¹

2013

CCBR

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Memory is a complex phenomenon due to a large number of potential interactions that are associated with the organization of memory at the psychological and neural system level. In this review article a tripartite, multiple attribute, multiple process memory model with different forms of memory and its neurobiological underpinnings is represented in terms of the nature, structure or content of information representation as a set of different attributes including language, time, place, response, reward value (affect) and visual object as an example of sensory-perception. For each attribute, information is processed in the event-based, knowledge-based, and rule-based memory systems through multiple operations that involve multiple neural underpinnings. Of the many processes associated with the event-based memory system, the emphasis will be placed on short-term or working memory and pattern separation. Of the many processes associated with the knowledgebased memory system, the emphasis will be placed on perceptual processes. Of the many processes associated with the rule-based memory system the emphasis will be on short-term or working memory and paired associate learning. For all three systems data will be presented to demonstrate differential neuroanatomical mediation and where available parallel results will be presented in rodents, monkeys and humans.

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Section: Short-term or Working Memory --Affect Attributementioning

confidence: 79%

Neurobiological foundations of an attribute model of memory

Kesner¹

2013

CCBR

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“…Later on, this attentional control was proposed to underlie the psychological function of internal inhibition (Douglas, 1972;Douglas & Pribram, 1966;Kimble, 1968). The internal inhibition hypotheses find serious difficulties in the fact that hippocampal ablations do not affect the formation of conditioned inhibition when training consisted of a stimulus A, always reinforced, interspersed with stimuli A and B, always nonreinforced (Solomon, 1977).…”

Section: Discussionmentioning

confidence: 99%

“…However, animals with hippocampal lesions would behave like normals in acquisition, conditioned inhibition, latent learning, passive avoidance, and retrograde memory tasks, to the extent that inhibition of the orienting response is not involved in these tasks. Douglas and Pribram (1%6), Kimble (1968), and Douglas (1972): Attentional Control and Internal Inhibition Douglas and Pribram (1966) proposed that the hippocampus excluded stimuli from attention through efferent control of sensory reception. This control would inhibit the reception of stimuli that have been associated with nonreinforcement, constituting a restatement of Pavlov's (1927) internal inhibition in attentional terms (Douglas, 1967).…”

Section: Theories Involving Attentional Mechanismsmentioning

confidence: 99%

“…This mechanism decreases attention to nonreinforced stimuli in Douglas and Pribram's and Douglas's models, but shifts attention from one stimulus to another in Kimble's model. Douglas and Pribram's (1966), Kimble's (1968), and Douglas's (1972) models predict deficits in tasks in which internal inhibition is assumed to be involved. Habituation to novel stimuli, extinction, conditioned inhibition, and discrimination reversal would be retarded because, in these cases, the presentation of the stimulus followed by nonreinforcement would not generate internal inhibition, and therefore a persistence of responding would appear.…”

Section: Theories Of Hippocampal Function 167mentioning

confidence: 99%

“…Behavioral orienting reflex and hippocampal theta occur together. This view, correlating arousal or attention with the presence of theta rhythm, was first suggested by Green and Arduini (1954) and later adopted by Douglas and Pribram (1966).…”

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confidence: 98%

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Psychological theories of hippocampal function

Schmajuk

1984

Psychobiology

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Theories and models of the hippocampus have typically linked this structure to various psychological processes, for example, internal inhibition, response inhibition, attentional shift, attentional "tuning out," recognition memory, long-term memory selection, contextual retrieval, spatial memory, working memory, and chunking. Predictions made from various models are contrasted with reproducible hippocampal lesion data obtained from various experimental paradigms: habituation to novelty, acquisition, extinction, discrimination reversal, spontaneous alternation, latent inhibition, blocking, overshadowing, passive avoidance, maze learning, working memory procedures, latent learning, retrograde spatial memory, and conditioned inhibition. No single model correctly predicts all the empirical evidence. It is suggested that the hippocampal function, rather than subserving a unitary psychological function, might be better described as a computational-representational activity.

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