2013
DOI: 10.1253/circj.cj-12-1009
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Left Ventricular Diastolic Function Is Closely Associated With Mechanical Function of the Left Atrium in Patients With Paroxysmal Atrial Fibrillation

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Cited by 35 publications
(28 citation statements)
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“…In our current study, we propose that increased susceptibility to atrial remodeling attributed to more‐severe diastolic dysfunction of LV additionally exposes women to the risk of stroke in comparison with men. We have recently reported that degree of LA remodeling and LAA mechanical function in AF are closely related to LV diastolic dysfunction 12. Other studies have demonstrated that LV diastolic function is more likely to be found in women7 because of their tendency toward central aortic stiffness and increased susceptibility to load‐dependent LV diastolic dysfunction 9.…”
Section: Discussionmentioning
confidence: 97%
See 1 more Smart Citation
“…In our current study, we propose that increased susceptibility to atrial remodeling attributed to more‐severe diastolic dysfunction of LV additionally exposes women to the risk of stroke in comparison with men. We have recently reported that degree of LA remodeling and LAA mechanical function in AF are closely related to LV diastolic dysfunction 12. Other studies have demonstrated that LV diastolic function is more likely to be found in women7 because of their tendency toward central aortic stiffness and increased susceptibility to load‐dependent LV diastolic dysfunction 9.…”
Section: Discussionmentioning
confidence: 97%
“…Recently, it has been reported that women are more likely than men to have left ventricular (LV) diastolic dysfunction 7, 8, 9, 10. In previous studies, we have found that LV diastolic dysfunction is associated with the degree of left atrial (LA) electroanatomical remodeling and LA appendage (LAA) flow velocity (LAA‐FV), and that LA remodeling is associated with the risk and events of stroke in AF 11, 12. Based on these studies, we hypothesized that LA remodeling and poor contractile function of LAA are more predominant in women than men among AF patients with risk of stroke.…”
Section: Introductionmentioning
confidence: 99%
“…8,18,19 In contrast, SR was maintained in 13 of 16 patients (82%) with mild or moderate LV diastolic dysfunction (E/e' <15). In those patients, the LA pressure might not be so high and the LA remodeling might not progress very much after RFCA for AF.…”
Section: Diastolic Dysfunction and Rfca For Af With Hcmmentioning
confidence: 95%
“…Moreover, the functions of LA booster-pump were found to be related to symptoms of severe AS in patients with preserved LVEF [22]. Although the velocities of the E/E m and E m have a close relationship with systolic function, recent studies reported that this parameter reflected the functions of the LAA, independent of the LVEF [23][24][25].…”
Section: Discussionmentioning
confidence: 99%
“…In this study, a significant increase in the post-procedural LAA tissue Doppler velocities in the low LVEF group was detected. Different studies demonstrated depressed LA or LAA functions due to LV mass, LV outflow tract gradients, and LV diastolic dysfunction [22][23][24]. Moreover, the functions of LA booster-pump were found to be related to symptoms of severe AS in patients with preserved LVEF [22].…”
Section: Discussionmentioning
confidence: 99%