‘Liking’ and ‘wanting’ in eating and food reward: Brain mechanisms and clinical implications

Morales, Ileana; Berridge, Kent C.

doi:10.1016/j.physbeh.2020.113152

Cited by 201 publications

(167 citation statements)

References 381 publications

Supporting

Mentioning

156

Contrasting

Unclassified

Order By: Relevance

“…On the other hand, it has been reported that dopamine in the DS circuit can enhance the incentive salience of food reward cues, especially when foods are both caloric and palatable, thus implying that DS plays a role in "incentive motivation" (Fig. 1) [28,29].…”

Section: Article In Pressmentioning

confidence: 99%

Dopaminergic Control of the Feeding Circuit

Baik

2021

Endocrinol Metab

View full text Add to dashboard Cite

There is increasing evidence demonstrating that reward-related motivational food intake is closely connected with the brain's homeostatic system of energy balance and that this interaction might be important in the integrative control of feeding behavior. Dopamine regulates motivational behavior, including feeding behaviors, and the dopamine reward system is recognized as the most prominent system that controls appetite and motivational and emotional drives for food. It appears that the dopamine system exerts a critical role in the control of feeding behavior not only by the reward-related circuit, but also by contributing to the homeostatic circuit of food intake, suggesting that dopamine plays an integrative role across the converging circuitry of control of food intake by linking energy state-associated signals to reward-related behaviors. This review will cover and discuss up-to-date findings on the dopaminergic control of food intake by both the reward-related circuit and the homeostatic hypothalamic system.

show abstract

Section: Article In Pressmentioning

confidence: 99%

Dopaminergic Control of the Feeding Circuit

Baik

2021

Endocrinol Metab

View full text Add to dashboard Cite

show abstract

“…Weight loss (WL) through dietary energy restriction is thought to create a compensatory drive to overeat, which could potentially lead to weight regain [ 1 ]. Food reward which can be defined by its dual components of liking (pleasure from the food) and implicit wanting (cue-elicited motivation to eat) [ 2 , 3 , 4 , 5 ] has also been proposed to increase during WL. This belief is based on evidence from short-term energy restriction, which has been shown to increase hedonic responses to food [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

“…Indeed, liking and wanting are separable components of food reward with distinguishable brain systems [ 9 ], that may have independent roles in eating behavior and in characterizing susceptibility to weight gain [ 10 ]. Both liking and wanting are strong determinants of what we eat, but the hedonic value (liking) and the incentive motivation (wanting) can separate under specific situations (e.g., exercise, eating disorders) which remain to be studied [ 3 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Food Liking but Not Wanting Decreases after Controlled Intermittent or Continuous Energy Restriction to ≥5% Weight Loss in Women with Overweight/Obesity

et al. 2021

View full text Add to dashboard Cite

Food reward (i.e., liking and wanting) has been shown to decrease after different types of weight management interventions. However, it is unknown whether specific dietary modalities (continuous (CER) vs. intermittent (IER) energy restriction) have differing effects on liking and implicit wanting after weight loss (WL) and whether these changes are sustained after 1-year of no-contact. Women with overweight or obesity (age 18–55 years) were randomly allocated to controlled-feeding CER (25% daily energy restriction) or IER (alternating ad libitum and 75% energy restriction days). Study visits were conducted at baseline, post-WL (to ≥5% WL within 12 weeks) and 1-year post-WL. The main outcomes were liking and implicit wanting for 4 categories of common food varying in fat and taste assessed by the Leeds Food Preference Questionnaire. Linear mixed models were conducted on the 30 participants achieving ≥5% WL and 15 returners. After an initial WL of −5.1 ± 0.2 kg, after 1-year 2.6 ± 0.5 kg were regained. Liking but not wanting decreased after WL. Food reward after 1-year did not differ from baseline, but the high loss to follow-up prevents generalization. IER and CER did not differ in their effects on food reward during WL or at 1-year follow-up.

show abstract

“…Another component of the ventral striatum, the NAc, constitutes a critical node within mesocorticolimbic circuits that mediate “wanting” and “liking” ( Richard et al, 2013 ; Morales and Berridge, 2020 ). Pharmacological functional mapping revealed that local microcircuits of the NAc medial shell differentially regulate food intake of palatable chocolate and hedonic reactions to taste stimulation.…”

Section: Introductionmentioning

confidence: 99%

“…A notable difference between the OT and NAc is that the OT receives abundant synaptic inputs from the olfactory bulb and olfactory cortical areas ( Zhang et al, 2017b ), which convey olfactory sensory cues of food in the environment and olfactory components of flavors during mastication via the retronasal pathway to the OT. Indeed, the OT is considered the “striatum with olfactory function” ( Wesson and Wilson, 2011 ; Martin-Lopez et al, 2019 ) and may drive olfaction-based “wanting” and “liking” behaviors ( Richard et al, 2013 ; Morales and Berridge, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Hypothetical Roles of the Olfactory Tubercle in Odor-Guided Eating Behavior

Murata

2020

Front. Neural Circuits

View full text Add to dashboard Cite

Olfaction plays an important role in the evaluation, motivation, and palatability of food. The chemical identity of odorants is coded by a spatial combination of activated glomeruli in the olfactory bulb, which is referred to as the odor map. However, the functional roles of the olfactory cortex, a collective region that receives axonal projections from the olfactory bulb, and higher olfactory centers in odor-guided eating behaviors are yet to be elucidated. The olfactory tubercle (OT) is a component of the ventral striatum and forms a node within the mesolimbic dopaminergic pathway. Recent studies have revealed the anatomical domain structures of the OT and their functions in distinct odor-guided motivated behaviors. Another component of the ventral striatum, the nucleus accumbens, is well known for its involvement in motivation and hedonic responses for foods, which raises the possibility of functional similarities between the OT and nucleus accumbens in eating. This review first summarizes recent findings on the domain- and neuronal subtype-specific roles of the OT in odor-guided motivated behaviors and then proposes a model for the regulation of eating behaviors by the OT.

show abstract

‘Liking’ and ‘wanting’ in eating and food reward: Brain mechanisms and clinical implications

Cited by 201 publications

References 381 publications

Dopaminergic Control of the Feeding Circuit

Dopaminergic Control of the Feeding Circuit

Food Liking but Not Wanting Decreases after Controlled Intermittent or Continuous Energy Restriction to ≥5% Weight Loss in Women with Overweight/Obesity

Hypothetical Roles of the Olfactory Tubercle in Odor-Guided Eating Behavior

Contact Info

Product

Resources

About