Limb salvage in musculoskeletal oncology: Recent advances

Puri, Ajay

doi:10.4103/0970-0358.138937

Cited by 19 publications

(12 citation statements)

References 56 publications

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“…[ 8 ] The multitude of surgical procedures to reconstruct the bone defects following wide tumour resection are available. [ 9 ] These procedures have their own advantages and disadvantages.…”

Section: Discussionmentioning

confidence: 99%

Limb salvage with microvascular free fibula following primary bone sarcoma resection

Sahasrabudhe

Panchwagh

Rathod

et al. 2016

Indian J Plast Surg

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Background:Extremity sarcomas are challenging to manage. Total eradication of tumour has to be balanced with restoration of limb function to prevent mortality and morbidity. Disease-free survival with maximum limb function is the ultimate goal in these patients.Materials and Methods:We present a series of ten cases of extremity malignancies, where limb salvage was attempted with microvascular free fibula for limb reconstruction from the period of 2008 to 2015.Results:Of the ten cases in the study, there were two females and eight males. There were nine patients with lower limb malignancies and one patient with upper limb malignancy. There were four patients with Ewing's sarcoma of femur, five patients with osteosarcoma of femur and one patient with chondrosarcoma of the humerus. The follow-up period ranged from 1.2 to 6.2 years with mean follow-up of 3.1 years. There were two deaths during follow-up, both were due to distant metastasis. The assessment of the function was done on the basis of Musculoskeletal Tumour Society functional score. Maximum score was 30 and minimum score was 24, the average score being 26. Of the eight surviving patients, three patients had full weightbearing, four patients had partial weightbearing at end of 2 years and one patient of upper limb reconstruction had complete upper limb function. None of the patients had to undergo limb amputation.Conclusion:Limb salvage with vascularised fibula graft offers good functional outcome along with good disease-free survival rates.

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Section: Discussionmentioning

confidence: 99%

Limb salvage with microvascular free fibula following primary bone sarcoma resection

Sahasrabudhe

Panchwagh

Rathod

et al. 2016

Indian J Plast Surg

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“…Much is discussed about which type of surgical procedure is most appropriate for tumor resection with wide margins together with healthy tissues. ( 2 ), ( 4 Due to complexity, the patient may present physical, functional limitations, psychological and emotional alterations. ( 5 …”

Section: Introductionmentioning

confidence: 99%

Quality of Life in Adults With Sarcomas Under Conservative Surgery or Amputation

Silva

Tabet²,

Batista³

et al. 2020

Acta ortop. bras.

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Objective: To understand the perception of quality of life, functionality, and psychological aspects of adults with lower limb sarcoma who underwent conservative surgery or amputation. Methods: Sociodemographic data were collected, and the following questionnaires were used: EORTC QLQ - C30 for quality of life, the Functional Assessment System (MSTS) for functionality and the Beck Depression Inventory (BDI) for depression symptoms. Results: The sample consisted of 45 young adults with sarcoma, divided into two groups: amputation (29) and conservative surgery (16). Most were male, single and students. Average family income before and after the disease did not differ, but those that were employed had a better perception of general quality of life, as well as those with higher family income after the disease. Regarding the type of surgery, there was a predominance of amputation; osteosarcoma was the most common histological type and the most affected region was the femur. All participants participated in social, cultural, sporting or religious activities. MSTS and Beck scale values did not differ between procedures. Conclusion: Given the scarcity of studies on the subject at the national level, further investigations are suggested to explore aspects related to quality of life for patients with sarcomas. Level of Evidence III, Retrospective comparative study.

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“…This survival is long enough to justify the complex procedures in limb sparing surgery. At this era, limb-salvage procedures are the gold standard for most of the cases [3]. Amputation is recommended in very selective patients and cases.…”

Section: Introductionmentioning

confidence: 99%

Malignant distal femur tumors management in children, low cost innovations with affordable care in a tertiary care hospital, a cross sectional study

Saeed

Husseinali

2019

Annals of Medicine and Surgery

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Introduction Malignant musculoskeletal tumors in children are mostly comprised of Osteosarcoma and Ewing's sarcoma and distal femur is the most common site for primary bone tumors. This study examined the surgical management outcomes of pediatric patients (<18 years) presented in our setup with malignant distal femur tumors. Methodology We retrospectively reviewed the medical records of patients diagnosed with malignant sarcomas of distal femur and younger than 18 years of age who underwent limb salvage surgery during June 2009–June2017. Results There were 31 pediatric patients who had distal femur malignant tumors and out of them 20 patients were selected who underwent limb salvage as a primary surgery. The mean age (range) of patients was 11.90 (6–17) years. Seventeen had osteosarcoma and three had Ewing's sarcoma. In surgery all patients were offered reconstruction. Post-operative complications were observed in (50%) patients while other 50% patients had no complications. Wound infection, flap necrosis, broken plates with non-union and recurrence of disease were the reported complications. Revision surgery was performed in 10 patients out of 20 patients. Conclusion Salvage was the primary option in our surgery and revision surgery was performed in the cases due to complications. Small sample size was the limitation of the study.

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Limb salvage in musculoskeletal oncology: Recent advances

Cited by 19 publications

References 56 publications

Limb salvage with microvascular free fibula following primary bone sarcoma resection

Limb salvage with microvascular free fibula following primary bone sarcoma resection

Quality of Life in Adults With Sarcomas Under Conservative Surgery or Amputation

Malignant distal femur tumors management in children, low cost innovations with affordable care in a tertiary care hospital, a cross sectional study

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