Linking individual differences in human V1 to perception around the visual field

Himmelberg, Marc M.; Winawer, Jonathan; Carrasco, Marisa

doi:10.21203/rs.3.rs-1065719/v1

Cited by 4 publications

(2 citation statements)

References 85 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is possible that individual variation in the distribution (as opposed to overall quantity) of retinal cell populations over eccentricity or polar angle may be reflected in the visual cortex. Indeed, recent work has shown that polar angle variation in group and individual measures of perception are related to variation in cortical magnification across area V1 (Benson et al, 2021; Himmelberg, et al, 2021; Kupers et al, 2022).…”

Section: Discussionmentioning

confidence: 99%

Retinal ganglion cell endowment is correlated with optic tract fiber cross section, not density

Taskin

Qiao

Sydnor

et al. 2022

Preprint

View full text Add to dashboard Cite

There is substantial variation between healthy individuals in the number of retinal ganglion cells (RGC) in the eye, with commensurate variation in the number of axons in the optic tracts. Fixel-based analysis of diffusion MR produces estimates of fiber density (FD) and cross section (FC). Using these fixel measurements along with retinal imaging, we asked if individual differences in the estimated number of RGCs are correlated with individual differences in FD and FC measurements obtained from the optic tracts, and subsequent structures along the cortical visual pathway. We find that RGC endowment is correlated with optic tract FC, but not with FD. RGC cell number had a decreasing relationship with measurements from subsequent regions of the visual system (LGN volume, optic radiation FC/FD, and V1 surface area). However, we also found that the variations in each visual area were correlated with the variations in its immediately adjacent visual structure. We only observed these serial correlations when FC is used as the measure of interest for the optic tract and radiations, but no significant relationship was found when FD represented these white matter structures. From these results, we conclude that the variations in RGC endowment, LGN volume, and V1 surface area are better predicted by the overall cross section of the optic tract and optic radiations relative to the intra-axonal restricted signal component of these white matter pathways. Additionally, the presence of the significant correlations between adjacent, but not distant, anatomical structures suggest that there are multiple, local sources of anatomical variation along the visual pathway.

show abstract

Section: Discussionmentioning

confidence: 99%

Retinal ganglion cell endowment is correlated with optic tract fiber cross section, not density

Taskin

Qiao

Sydnor

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…These individual differences are not explained by variation in whole brain size (Andrews et al, 1997;Benson et al, 2021). Moreover, some studies have found that individual differences in V1 size can be related to properties of visual perception (Duncan and Boynton, 2003;Schwarzkopf et al, 2011;Song et al, 2013Song et al, , 2015Genç et al, 2015;Bergmann et al, 2016;Himmelberg et al, 2021). Understanding what factors influence individual differences in V1 size is likely to clarify our understanding of how human visual processing and perception vary across people.…”

Section: Introductionmentioning

confidence: 99%

Structural Covariance and Heritability of the Optic Tract and Primary Visual Cortex in Living Human Brains

et al. 2022

View full text Add to dashboard Cite

show abstract

Presaccadic attention enhances contrast sensitivity, but not at the upper vertical meridian

Hanning

Himmelberg

Carrasco

2021

Preprint

Self Cite

View full text Add to dashboard Cite

Human visual performance is not only better at the fovea and decreases with eccentricity, but also has striking radial asymmetries around the visual field: At a fixed eccentricity, it is better along (1) the horizontal than vertical meridian and (2) the lower than upper vertical meridian. These asymmetries, known as performance fields, are pervasive -they emerge for many visual dimensions, regardless of head rotation, stimulus orientation or display luminance- and resilient -they are not alleviated by covert exogenous or endogenous attention, deployed in the absence of eye movements. Performance fields have been studied exclusively during eye fixation. However, a major driver of everyday attentional orienting is saccade preparation, during which visual attention automatically shifts to the future eye fixation. This presaccadic shift of attention is considered strong and compulsory, and relies on fundamentally different neural computations and substrates than covert attention. Given these differences, we investigated whether presaccadic attention can compensate for the ubiquitous performance asymmetries observed during eye fixation. Our data replicate polar performance asymmetries during fixation and document the same asymmetries during saccade preparation. Crucially, however, presaccadic attention enhanced contrast sensitivity at the horizontal and lower vertical meridian, but not at the upper vertical meridian. Thus, instead of attenuating polar performance asymmetries, presaccadic attention exacerbates them.

show abstract

Linking individual differences in human V1 to perception around the visual field

Cited by 4 publications

References 85 publications

Retinal ganglion cell endowment is correlated with optic tract fiber cross section, not density

Retinal ganglion cell endowment is correlated with optic tract fiber cross section, not density

Structural Covariance and Heritability of the Optic Tract and Primary Visual Cortex in Living Human Brains

Presaccadic attention enhances contrast sensitivity, but not at the upper vertical meridian

Contact Info

Product

Resources

About