Diagnostics of disorders of reproductive function has certain complications and difficulties, especially in case of hidden course and subclinical manifestation, which requires laboratory tests. Therefore, the purpose of our work was to determine the biochemical parameters of the blood of infertile cows of a small farm and to interpret the obtained data regarding the effect on reproductive function.The research was carried out in the conditions of the «Horns and Hoofs firm» of the Novomoskovsk district of the Dnipropetrovsk region on cows of the black and spotted breed during the winter-stall period and the scientific research center of biosafety and ecologicalcontrol of agricultural resources "Biosafety center" in the city of Dnipro. The object of research was cows with impaired reproductive function, the subject was biochemical indicators of their blood. According to the results of the research, changes in biochemical indicators were found in the blood of infertile cows, which consisted in the deficiency of globulins (27.9 g/l), urea nitrogen (5.65 mg%), glucose (2.19 mmol/l), calcium (2.02 mmol/l), inorganic phosphorus (1.21 mmol/l), carotene (274.5 μg%) and selenium (22.14 μg/l); decrease to the limit content of urea (2.94 mmol/l), vitamins A (28.31 μg/100 ml) and E (3.84 μg/ml), copper (52.98 μg%) and cobalt (2.21 μg%); exceeding the normal content of AST (81.3 Units/l), manganese (39.44 µg%), protein coefficient (1.19 units), Ca/P (1.76 units) and total lipoproteins (1057.4 mg%). The specified changes can affect the manifestation of the reproductive capacity of animals and lead to delayed puberty and sexual maturity (deficiency of phosphorus, copper, cobalt), deterioration of the motor function of the muscles of the genital tract (deficiency of glucose, urea, vitamin E, selenium), violation of the sexual cycle anaphrodisia / anestrus (subestrus) / infertility (deficiency of urea, carotene / vitamins A and E, selenium, copper, cobalt, calcium, phosphorus, violation of the Ca:P ratio), increased insemination/fertilization index (deficiency of globulins, urea, carotene/vitamin A and E, selenium, copper, cobalt, calcium, phosphorus, violation of the Ca:P ratio), reduction of fertilization of eggs in vitro (glucose deficiency), violation of embryogenesis (deficiency of copper, cobalt, calcium, phosphorus, vitamins E and selenium) and processes fetal maturation (deficiency of globulins, copper), antenatal pathologies (deficiency of carotene/vitamin A), abortions (deficiency of urea, calcium, phosphorus, cobalt, copper), increased frequency of dystocia (deficiency of urea, carotene/vitamin A and E, selenium, copper) a violation of the Ca:P ratio), the birth of dead, weak or non-viable calves (deficiency of globulins, vitamins A and E, selenium, cobalt, copper, phosphorus), an increase in the number of postpartum diseases (deficiency of carotene/vitamin A and E, selenium, cobalt, calcium, phosphorus, violation of the Ca:P ratio), lengthening of the intercalary period (deficiency of glucose and phosphorus, violation of the Ca:P ratio).
Key words: female cattle, disorders of reproductive function, nutrients, vitamins, macro- and microelements.