Location of proliferating gingival cells following toothbrushing stimulation

Tomofuji, Takaaki; Sakamoto, Tomonori; Ekuni, Daisuke; Yamamoto, Tatsuo; Watanabe, Tatsuo

doi:10.1111/j.1601-0825.2006.01250.x

Cited by 6 publications

(12 citation statements)

References 17 publications

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“…Therefore, it may be considered that the improvement in liver injury might be incomplete ( Figure 2). One possible explanation is that LPS and proteases can stimulate production of TNF-a and ROS within both the gingival connective tissue subjacent to the junctional epithelium and the periodontal ligament [15], but the histological improvement by toothbrushing may be limited to connective tissue subjacent to the junctional epithelium [16]. In addition to toothbrushing, periodontal treatment that reaches the periodontal ligament (i.e.…”

Section: Discussionmentioning

confidence: 99%

Effects of improvement in periodontal inflammation by toothbrushing on serum lipopolysaccharide concentration and liver injury in rats

Tomofuji

Ekuni

Sanbe

et al. 2009

Acta Odontologica Scandinavica

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Section: Discussionmentioning

confidence: 99%

Effects of improvement in periodontal inflammation by toothbrushing on serum lipopolysaccharide concentration and liver injury in rats

Tomofuji

Ekuni

Sanbe

et al. 2009

Acta Odontologica Scandinavica

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“…Mechanical stimulation by toothbrushing is capable of inducing keratinization of the oral sulcular epithelium 8 , enhance gingival circulation 50 , cause formation of procollagen synthesis of gingival fibroblasts, and increase alveolar bone 53 . In addition, it has been shown that proliferation of basal cells, fibroblasts and synthesis of procollagen I are promoted more effectively by mechanical stimulation with a toothbrush than by removal of dental plaque 24 .…”

Section: Introductionmentioning

confidence: 99%

Non-inflammatory destructive periodontal disease: a clinical, microbiological, immunological and genetic investigation

Repeke¹,

Cardoso

Claudino

et al. 2012

J. Appl. Oral Sci.

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Periodontitis comprises a group of multifactorial diseases in which periodontopathogens accumulate in dental plaque and trigger host chronic inflammatory and immune responses against periodontal structures, which are determinant to the disease outcome. Although unusual cases of non-inflammatory destructive periodontal disease (NIDPD) are described, their pathogenesis remains unknown. A unique NIDPD case was investigated by clinical, microbiological, immunological and genetic tools. The patient, a non-smoking dental surgeon with excessive oral hygiene practice, presented a generalized bone resorption and tooth mobility, but not gingival inflammation or occlusion problems. No hematological, immunological or endocrine alterations were found. No periodontopathogens (A. actinomycetemcomitans, P. gingivalis, F. nucleatum and T. denticola) or viruses (HCMV, EBV-1 and HSV-1) were detected, along with levels of IL-1β and TNF-α in GCF compatible with healthy tissues. Conversely ALP, ACP and RANKL GCF levels were similar to diseased periodontal sites. Genetic investigation demonstrated that the patient carried some SNPs, as well HLA-DR4 (*0404) and HLA-B27 alleles, considered risk factors for bone loss. Then, a less vigorous and diminished frequency of toothbrushing was recommended to the patient, resulting in the arrest of alveolar bone loss, associated with the return of ALP, ACP and RANKL in GCF to normality levels. In conclusion, the unusual case presented here is compatible with the previous description of NIDPD, and the results that a possible combination of excessive force and frequency of mechanical stimulation with a potentially bone loss prone genotype could result in the alveolar bone loss seen in NIDPD.

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“…Fibroblast as the most predominant cell in connective tissue are engaged in production of collagen fibers. 9 Before and after study in toothpick method group revealed significant difference which meant that toothpick toothbrushing method was able to increase 0HI-S, decrease GI and BOP; the same result occured with control group (p = 0.001; p < 0.05). Increase of OHI-S index accompanied with increase of gingival index, BOP and pocket depth from toothpick method group was caused by the improvement of dental plaque control pattern with toothpick toothbrushing method.…”

Section: Discussionmentioning

confidence: 75%

“…With toothpick toothbrushing method, stimulation proliferation basal cells would reduce gingival bleeding in gingivitis and periodontitis. 9 Other possibility was the healing effect from scaling therapy. Previous studies revealed the decrease of PD after initial treatment the change of PD condition was influenced by several factors which interrelated to each other.…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, if considering the difference of Means in OHI-S, GI, BOP and PD before and after treatment, in toothpick group had greater value compared to control group (p < 0.05) ( Table 3). Toothbrushing promotes the proliferation activity of gingival cells adjacent to the cementum, gingival and the alveolar bone 9 . Proliferation of fibroblasts were consistent with stress distribution at toothbrushing, but no effects on proliferation of periodontal ligament.…”

Section: Discussionmentioning

confidence: 99%

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The effectivity of toothpick tooth brushing method on plaque control

Prahasanti

Ruhadi

Mulyana

2011

Dent. J. (Majalah Kedokteran Gigi)

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Background: Periodontal diseases are associated with bacteria species which present in biofilms that colonize on dental surfaces. Several tooth brushing methods had been known and proved to be effective in maintaining oral hygiene. Among them, tooth pick technique was a relatively new method and its superiority in removing interproximal plaque was better than other methods. Purpose: The purpose of this study was to examine the effectivity of toothpick tooth brushing method to conventional method on periodontal health. Methods: This research was designed as an analytical observational study. Thirty samples selected from five hundred and twelve males Indonesian Air-force members in Malang, aged 18-40 yrs, with periodontal pockets (≤ 5 mm) in upper or lower teeth, without crowding, gingival index minimal > 1 (moderate gingivitis), OHI-S score minimal ≥ 1.3 (moderate), without systemic diseases, do not undergone medical therapy/drug prescriptions, without using mouth rinse during study, and without prosthesis. There were thirty samples in this research and devided to two groups, fifteen samples easch. The groups were toothpick tooth brusing method and conventional method (control group). In this study oral hygiene index simplified (OHI-S), gingival index (GI), bleeding on probing (BOP) and pocket depth were examined. Results: There were significant differences (p = .001) in OHI-S, GI, BOP, and PD before and after conducting each toothbrushing method, as well as differences between means (quarrel means), that were p = .003; p = .001; p = .001 and p = .001 consecutively. Conclusion: Toothpick brushing method was more effective in plaque control compared to conventional method.

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Location of proliferating gingival cells following toothbrushing stimulation

Abstract: Toothbrushing promotes proliferation of gingival cells other than fibroblasts in periodontium and basal cells in the apical portion of the junctional epithelium. The repair of periodontal tissues might be promoted by toothbrushing within the limit of the direct mechanical stimulation.

Cited by 6 publications

References 17 publications

Effects of improvement in periodontal inflammation by toothbrushing on serum lipopolysaccharide concentration and liver injury in rats

Effects of improvement in periodontal inflammation by toothbrushing on serum lipopolysaccharide concentration and liver injury in rats

Non-inflammatory destructive periodontal disease: a clinical, microbiological, immunological and genetic investigation

The effectivity of toothpick tooth brushing method on plaque control

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