With increasing depth of exploration and process boreholes (at small drilling diameters), the probability of deviation of the borehole path from design trajectory increases many times; i. e. zenith curvature and azimuth deviation of the borehole path occur. Therefore, developing methods for keeping vertical path of the borehole when drilling deeper horizons of ore bodies is a very topical issue. The paper presents the results of developing a new bottom-hole assembly for drilling boreholes in soft rocks using screw casing centralizers, which provide good stabilizing and centering effects to mitigate horizontal departure of the hole axis from the design direction and minimize vertical curvature of the hole path (zenith angle) while maintaining sufficient drill string flexibility. The developed technical solutions provide simplicity of design and ability to adapt to wide range of mining, geological and technological drilling conditions. The feasibility of manufacturing the centralizers by own efforts and the technological feasibility of quick and easy connecting the centralizer with other elements of the bottom-hole assembly have been substantiated. The manufacture efficiency is proved by the use of inexpensive and wear-resistant materials in the centralizer armouring, for which tungsten-cobalt or titanium-cobalt hard-alloy inserts were used. In addition, prevailing volume of borehole drilling in soft rocks allowed using replaceable centering elements, as well as their repair and restoration to increase their service life. The manufactured centralizer has a low production cost due to the design simplicity and the use of inexpensive wearresistant material and will compete in the market of drilling tools and technical devices for drill string stabilization. The economic effect from the introduction of the self-produced centralizers amounted to more than 170,000 tenge per a borehole.