Long‐Term Generation of Longitudinal Spin Order Controlled by Ammonia Ligation Enables Rapid SABRE Hyperpolarized 2D NMR

Abstract

The front cover artwork front cover artwork is provided by NMRCoRe, the Flemish NMR/X‐Ray platform for Convergence Research and was designed by Ir. Ewoud Vaneeckhaute and Dr. Eric Breynaert. The image shows the reciprocity between parahydrogen, deuterated ammonia and iridium allowing for hyperpolarized 2D NMR via long‐term availability of longitudinal spin order. Read the full text of the Article at 10.1002/cphc.202100079.

Isotopological Fingerprinting Using 1H/D Scrambling Identifies the Stereochemistry of Hyperpolarization Catalysts Transferring Spin Polarization from Parahydrogen to Substrates Using Signal Amplification by Reversible Exchange

“…The reciprocal chemical shift translation of fingerprints points to a variation in the substitution of the axial position. In this case, pyridine is exchanged for ammonia, an assignment substantiated by elucidation of a similar catalytic system previously described by Vaneeckhaute et al 27 Hence, although axial substitution is not reflected directly in the isotopological fingerprint, translation can empirically hint to the chemical nature of the axial ligand.…”

“…Hydrides, originating from parahydrogen that have been oxidatively added to a transition metal, are typically used to highlight particular stereoconformations of the catalyst (Figure a). , In 1 H-NMR, resonances associated with hydrides present on a transition metal complex are observed at negative chemical shifts, fully separated from other 1 H-NMR signals in the system and therefore easily recognized. − Depending on the substrates involved in the catalytic process, association of the ligands provides a dispersion of hydride shifts that reports on stereochemistry of the catalytic complex. − …”

Методы Получения Поляризованного Ксенона Для Магнитно-Резонансной Томографии (Обзор)

“…Способы получения гиперполяризованных ядерных спинов в твердых телах, жидкостях и газах описаны в ряде обзоров и монографий [5][6][7][8], которые включают Brute−Force Hyperpolarization [9], оптическую накачку со спиновым обменом (SEOP) [10], динамическую ядерную поляризацию (DNP) [11], химически индуцированную динамическую ядерную поляризацию (CIDNP) [12], фото-CIDNP [13], поляризацию, индуцированную параводородом (PHIP) [14] и усиление сигнала путем обратимого обмена (SABRE) [15].…”

Methods for obtaining polarized xenon for magnetic resonance imaging. Review

“…Methods for obtaining hyperpolarized nuclear spins in solids, liquids and gases are described in a number include of reviews and monographs [5][6][7][8], which the Brute−Force Hyperpolarization [9], spin exchange optical pumping (SEOP) [10], dynamic nuclear polarization (DNP) [11], chemically induced dynamic nuclear polarization (CIDNP) [12], photo -CIDNP [13], parahydrogeninduced polarization (PHIP) [14] and signal amplification by reversible exchange (SABRE) [15].…”