Long-Term Outcome of Argon Plasma Ablation Therapy for Bleeding in 100 Consecutive Patients with Colonic Angiodysplasia

Olmos, Jorge; Marcolongo, Mariano; Pogorelsky, Valeria; Herrera, Leandro; Tobal, Federico; Dávolos, Jorge

doi:10.1007/s10350-006-0684-1

Cited by 85 publications

(65 citation statements)

References 36 publications

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“…In the present study, the mean age of patients with bleeding colonic AGD was 84 years, which is older than that observed in previous studies [7]. In addition, all patients had chronic heart disease, including chronic heart failure, atrial fibrillation, and coronary artery disease or a post-aortic valve replacement or post-mitral valve replacement status.…”

Section: Discussioncontrasting

confidence: 52%

Clinical features and endoscopic findings in patients with actively bleeding colonic angiodysplasia

Nishimura

Matsueda

Hamaguchi

et al. 2015

Indian J Gastroenterol

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Colonic angiodysplasia (AGD) is an important cause of lower gastrointestinal bleeding. However, most episodes of bleeding from colonic AGD stop spontaneously. To date, few data are available regarding the endoscopic findings of bleeding colonic AGD. In order to clarify the clinical features and endoscopic findings of actively bleeding colonic AGD, we conducted a retrospective study of patients treated with colonoscopy at our hospital. From November 2006 to March 2013 inclusive, 32,586 colonoscopies were performed at this hospital, among which 13 patients with bleeding colonic AGD were enrolled in the current study. The mean age was 84 years (range: 69-90 years). All patients had chronic heart disease and were currently using anticoagulant and/or antiplatelet drugs. Sites of bleeding AGD were localized in the left colon in two patients (15 %) and in the right colon in the remaining patients (85 %). A total of 77 % of the lesions (10/13) were 1-2 mm in size and two lesions were 4 mm in size; only one lesion was larger than 5 mm. Endoscopic treatment resulted in a therapeutic success rate of 100 %, and no recurrence of bleeding was observed in 85 % of the patients (11/13) after treatment. During the study period, two patients presented with bleeding from residual AGD and underwent endoscopic treatment. In the present study, most sites of bleeding colonic AGD were very small, termed "micro-angiodysplasia", and targeted endoscopic treatment for actively bleeding AGD was found to be effective and safe. It is essential that physicians consider the potential for actively bleeding colonic AGD, especially "micro-angiodysplasia", when performing colonoscopy in elderly patients with a history of cardiovascular disease and/or treatment with anticoagulant or antiplatelet therapy.

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Section: Discussioncontrasting

confidence: 52%

Clinical features and endoscopic findings in patients with actively bleeding colonic angiodysplasia

Nishimura

Matsueda

Hamaguchi

et al. 2015

Indian J Gastroenterol

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“…It can be directed to specific pathologic mucosa and can cover an expanded area in paintbrush-like fashion. Olmos et al [13] reported a bleed-free period of 2 years for up to 90% of patients after using APC for angiodysplasia. Energy targeting and dosimetry, however, are entirely operator controlled.…”

Section: Discussionmentioning

confidence: 99%

A feasibility and dosimetric evaluation of endoscopic radiofrequency ablation for human colonic and rectal epithelium in a treat and resect trial

et al. 2010

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Endoscopic RFA is capable of delivering therapy to the distal colon. Injury is limited to the muscularis propria or less depth when no more than two ablations are applied regardless of the energy density used. Based on these feasibility and dosimetry results, the authors will continue investigation using these and smaller energy doses to initiate trials ultimately with patients who have suitable mucosal and submucosal disorders of the lower gastrointestinal tract including chronic, nonulcerated hemorrhagic radiation proctitis and angiodyplasia.

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“…Bizim vakamızın APC yöntemiyle beraber destek tedavisine verdiği hızlı cevap APC'nin HHT'ye bağlı anjiodisplazik lezyonlarda seçkin tedavi yöntemi olduğu görüşünü desteklemektedir (22)(23)(24). Yapılan yayınları incelediğimizde HHT'li olgularda özellikle endoskopik ve farmakolojik tedavi kombinasyonun uygulandığı prospektif bir çalışmanın olmaması bu alandaki bilgilerimizi sınırlamaktadır.…”

Section: Discussionunclassified

Herediter hemorajik telenjektazili bir vakanın, argon plazma koagülasyonu ve destek tedavisi kombinasyonuyla başarılı yönetimi

Yeşıl¹,

Şenateş²,

Kayataş³

et al. 2015

Endoskopi Gastrointestinal

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Long-Term Outcome of Argon Plasma Ablation Therapy for Bleeding in 100 Consecutive Patients with Colonic Angiodysplasia

Abstract: Endoscopic argon plasma ablation therapy is useful in the management of bleeding from colonic angiodysplasia.

Cited by 85 publications

References 36 publications

Clinical features and endoscopic findings in patients with actively bleeding colonic angiodysplasia

Clinical features and endoscopic findings in patients with actively bleeding colonic angiodysplasia

A feasibility and dosimetric evaluation of endoscopic radiofrequency ablation for human colonic and rectal epithelium in a treat and resect trial

Herediter hemorajik telenjektazili bir vakanın, argon plazma koagülasyonu ve destek tedavisi kombinasyonuyla başarılı yönetimi

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