Long-Term Prognosis of Patients With Coronary Microvascular Disease Using Stress Perfusion Cardiac Magnetic Resonance

Zhou, Wenli; Lee, Jonan Chun Yin; Leung, Siu Ting; Lai, Alta Y T; Lee, Tang-fei; Chiang, Jeanie Betsy; Cheng, Yuet Wong; Chan, Hiu-Lam; Yiu, Kai‐Hang; Goh, Victor; Pennell, Dudley J.; Ng, Ming-Yen

doi:10.1016/j.jcmg.2020.09.034

Cited by 73 publications

(43 citation statements)

References 35 publications

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“…Though little research has been done using perfusion CMR, recent studies have shown that MPRI derived from CMR, expressed as the hyperemic-to-resting myocardial perfusion ratio, can evaluate the prognosis of patients. In a retrospective study of 218 patients by Zhou et al ( 68 ), 91% of the patients had an MPRI value of <2.0. During the 5.5-year follow-up, 34 MACEs occurred, an MPRI cut-off value of <1.47 was identified as the optimal prognostic threshold for predicting MACE.…”

Section: Research Progress Of Imaging Methods For Detection Of Microvascular Angina Pectorismentioning

confidence: 99%

Research Progress of Imaging Methods for Detection of Microvascular Angina Pectoris in Diabetic Patients

Feng

et al. 2021

Front. Cardiovasc. Med.

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Diabetes is a complex metabolic disease characterized by hyperglycemia. Its complications are various, often involving the heart, brain, kidney, and other essential organs. At present, the number of diabetic patients in the world is growing day by day. The cardiovascular disease caused by diabetes has dramatically affected the quality of life of diabetic patients. It is the leading cause of death of diabetic patients. Diabetic patients often suffer from microvascular angina pectoris without obstructive coronary artery disease. Still, there are typical ECG ischemia and angina pectoris, that is, chest pain and dyspnea under exercise. Unlike obstructive coronary diseases, nitrate does not affect chest pain caused by coronary microvascular angina in most cases. With the increasing emphasis on diabetic microvascular angina, the need for accurate diagnosis of the disease is also increasing. We can use SPECT, PET, CMR, MCE, and other methods to evaluate coronary microvascular function. SPECT is commonly used in clinical practice, and PET is considered the gold standard for non-invasive detection of myocardial blood flow. This article mainly introduces the research progress of these imaging methods in detecting microvascular angina in diabetic patients.

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Section: Research Progress Of Imaging Methods For Detection Of Microvascular Angina Pectorismentioning

confidence: 99%

Research Progress of Imaging Methods for Detection of Microvascular Angina Pectoris in Diabetic Patients

Feng

et al. 2021

Front. Cardiovasc. Med.

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“…Recently, the prognostic value of MVD assessment by CMR was investigated. In a cohort of 218 patients with angina and without overt CAD, Zhou W et al demonstrated that CMR-derived MPR index was an independent predictor of adverse events [ 39 ]. Finally, in research settings, CMR was also used for the anatomic assessment of epicardial coronary vessels [ 40 ].…”

Section: Cardiovascular Mrimentioning

confidence: 99%

Coronary Microvascular Dysfunction: PET, CMR and CT Assessment

Tonet

Pompei

Faragasso³

et al. 2021

JCM

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Microvascular dysfunction is responsible for chest pain in various kinds of patients, including those with obstructive coronary artery disease and persistent symptoms despite revascularization, or those with myocardial disease without coronary stenosis. Its diagnosis can be performed with an advanced imaging technique such as positron emission tomography, which represents the gold standard for diagnosing microvascular abnormalities. In recent years, cardiovascular magnetic resonance and cardiac computed tomography have demonstrated to be emerging modalities for microcirculation assessment. The identification of microvascular disease represents a fundamental step in the characterization of patients with chest pain and no epicardial coronary disease: its identification is important to manage medical strategies and improve prognosis. The present overview summarizes the main techniques and current evidence of these advanced imaging strategies in assessing microvascular dysfunction and, if present, their relationship with invasive evaluation.

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“…In patients with ischemic symptoms but no significant CAD, stress perfusion CMR was found to be an independent predictor of major adverse cardiovascular events [ 52 ]. Furthermore, the role of dobutamine CMR can also be utilized to assess the functional significance of anomalous coronaries, although physiological exercise CMR if available is the preferred modality.…”

Section: Role Of Cmr In the Risk Stratification Of Patients With Cadmentioning

confidence: 99%

Contemporary Role of Cardiac Magnetic Resonance in the Management of Patients with Suspected or Known Coronary Artery Disease

et al. 2021

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Cardiac magnetic resonance imaging (CMR) is a useful non-invasive radiation-free imaging modality for the management of patients with coronary artery disease (CAD). CMR cine imaging provides the “gold standard” assessment of ventricular function, late gadolinium enhancement (LGE) provides useful data for the diagnosis and extent of myocardial scar and viability, while stress imaging is an established technique for the detection of myocardial perfusion defects indicating ischemia. Beyond its role in the diagnosis of CAD, CMR allows accurate risk stratification of patients with established CAD. This review aims to summarize the data regarding the role of CMR in the contemporary management of patients with suspected or known coronary artery disease.

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Long-Term Prognosis of Patients With Coronary Microvascular Disease Using Stress Perfusion Cardiac Magnetic Resonance

Cited by 73 publications

References 35 publications

Research Progress of Imaging Methods for Detection of Microvascular Angina Pectoris in Diabetic Patients

Research Progress of Imaging Methods for Detection of Microvascular Angina Pectoris in Diabetic Patients

Coronary Microvascular Dysfunction: PET, CMR and CT Assessment

Contemporary Role of Cardiac Magnetic Resonance in the Management of Patients with Suspected or Known Coronary Artery Disease

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