“…11 The physical, chemical and biological properties of calcium orthophosphate bioceramics and the fibrin glue might cumulate in biocomposites suitable for preparation of advanced bone grafts. [861][862][863][864][865][866][867][868][869][870][871][872][873] Furthermore, there are biocomposites of calcium orthophosphates with bisphosphonates, 874 silk fibroin (that is a hard protein extracted from silk cocoon), 312 885 and vitamins. 886 The reader's attention is also drawn to an interesting approach to crystallizing CDHA were not very good; due to a poor adhesion between the filler and the matrix, both the tensile strength and modulus were found to decrease with increase of the amount of HA.…”
“…11 The physical, chemical and biological properties of calcium orthophosphate bioceramics and the fibrin glue might cumulate in biocomposites suitable for preparation of advanced bone grafts. [861][862][863][864][865][866][867][868][869][870][871][872][873] Furthermore, there are biocomposites of calcium orthophosphates with bisphosphonates, 874 silk fibroin (that is a hard protein extracted from silk cocoon), 312 885 and vitamins. 886 The reader's attention is also drawn to an interesting approach to crystallizing CDHA were not very good; due to a poor adhesion between the filler and the matrix, both the tensile strength and modulus were found to decrease with increase of the amount of HA.…”
“…The 3D mesh of fibrin sealant interpenetrates the macro-and micro-porous structure of calcium orthophosphate ceramics [9]. The physical, chemical, and biological properties of calcium orthophosphate bioceramics and the fibrin glue might be cumulated in biocomposites, suitable for preparation of advanced bone grafts [707][708][709][710][711][712][713][714][715][716][717][718].…”
In this review article, the state-of-the-art of calcium orthophosphate-based biocomposites and hybrid biomaterials suitable for biomedical applications is presented.
“…has a high chemical stability, and does not cause inflammatory or antigenic reactions 1,5,17,19,21 . Another important property of synthetic hydroxyapatite is that its microstructure can be controlled to promote the formation of pores that can allow the migration of blood vessels and bone tissue into the material.…”
Section: Research and Emerging Technologies Osteobiologymentioning
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