Low 25-Hydroxyvitamin D and Myofascial Pain: Association of Cancer, Colon Polyps, and Tendon Rupture

Hightower, Jane M; Dalessandri, Kathie M.; Pope, Karl; Hernandez, German T.

doi:10.1080/07315724.2017.1320951

Cited by 8 publications

(5 citation statements)

References 58 publications

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“…Epidemiological studies conducted on colorectal cancer (CRC) provided strong support for inverse association between serum 25(OH)D level and colon cancer risk in both men and women 39 , 40 , 41 , 42 . A cross-sectional study indicated that low concentration of 25(OH)D in serum was significantly associated with adenomas or colon polyps 43 . A meta-analysis showed that higher circulating 25(OH)D levels predicted decrease cancer death of CRC patients 44 .…”

Section: Potentiating Vitamin D As An Anticancer Agentmentioning

confidence: 99%

Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment

Lü

et al. 2019

Acta Pharmaceutica Sinica B

113

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Tumor cells along with a small proportion of cancer stem cells exist in a stromal microenvironment consisting of vasculature, cancer-associated fibroblasts, immune cells and extracellular components. Recent epidemiological and clinical studies strongly support that vitamin D supplementation is associated with reduced cancer risk and favorable prognosis. Experimental results suggest that vitamin D not only suppresses cancer cells, but also regulates tumor microenvironment to facilitate tumor repression. In this review, we have outlined the current knowledge on epidemiological studies and clinical trials of vitamin D. Notably, we summarized and discussed the anticancer action of vitamin D in cancer cells, cancer stem cells and stroma cells in tumor microenvironment, providing a better understanding of the role of vitamin D in cancer. We presently re-propose vitamin D to be a novel and economical anticancer agent.

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Section: Potentiating Vitamin D As An Anticancer Agentmentioning

confidence: 99%

Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment

Lü

et al. 2019

Acta Pharmaceutica Sinica B

113

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show abstract

“…Günümüzde birçok hastalığın etiyolojisinde D vitamini eksikliği (DVE) olduğu düşünülmektedir (1)(2)(3)(4)(5)(6). Vitamin D 3 öncelikle deride sentezlenir ve karaciğerde hidroksillenerek 25 (OH) vitamin D'yi oluşturur (7)(8)(9)(10).…”

Section: Introductionunclassified

“…Erişkin yaşlarda patognomonik bulgusu bulunmamaktadır (11,13,16). Sıklıkla halsizlik, yorgunluk, duygu-durum bozukluğu, kaslarda huzursuzluk hissi, ağrı ve kramp tarzı belirtiler gösterebilir (1,3,10). D vitamini yetersizliğine bağlı oluşan osteomalazi kliniğinde genellikle lomber bölgeden başlayarak pelvis, uyluk, sırt ve kostaları içeren yaygın ağrılar görülür (3,14).…”

Section: Introductionunclassified

ssessment of the Relationship Between Vitamin D Level and Non-specific Musculoskeletal System Pain: A Multicenter Retrospective Study (Stroke Study Group)

Karahan¹,

Hüner²,

Kuran³

et al. 2017

Tod

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“…The role of magnesium as a cofactor for numerous enzymes, its impact on CNS function, and its ability to antagonize NMDA Glu receptors underscore its relevance in depression management [118,156,157]. Magnesium deficiency can lead to NMDA receptor hyperactivity, contributing to the development of depressive and anxiety-like symptoms and increased inflammatory markers [158].…”

Section: Magnesiummentioning

confidence: 99%

Trace Elements Levels in Major Depressive Disorder—Evaluation of Potential Threats and Possible Therapeutic Approaches

Baj,

Bargieł,

Cabaj

et al. 2023

IJMS

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The multifactorial etiology of major depressive disorder (MDD) includes biological, environmental, genetic, and psychological aspects. Recently, there has been an increasing interest in metallomic studies in psychiatry, aiming to evaluate the role of chosen trace elements in the MDD etiology as well as the progression of symptoms. This narrative review aims to summarize the available literature on the relationship between the concentration of chosen elements in the serum of patients with MDD and the onset and progression of this psychiatric condition. The authors reviewed PubMed, Web of Science, and Scopus databases searching for elements that had been investigated so far and further evaluated them in this paper. Ultimately, 15 elements were evaluated, namely, zinc, magnesium, selenium, iron, copper, aluminium, cadmium, lead, mercury, arsenic, calcium, manganese, chromium, nickel, and phosphorus. The association between metallomic studies and psychiatry has been developing dynamically recently. According to the results of current research, metallomics might act as a potential screening tool for patients with MDD while at the same time providing an assessment of the severity of symptoms. Either deficiencies or excessive amounts of chosen elements might be associated with the progression of depressive symptoms or even the onset of the disease among people predisposed to MDD.

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Low 25-Hydroxyvitamin D and Myofascial Pain: Association of Cancer, Colon Polyps, and Tendon Rupture

Cited by 8 publications

References 58 publications

Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment

Repurposing vitamin D for treatment of human malignancies via targeting tumor microenvironment

ssessment of the Relationship Between Vitamin D Level and Non-specific Musculoskeletal System Pain: A Multicenter Retrospective Study (Stroke Study Group)

Trace Elements Levels in Major Depressive Disorder—Evaluation of Potential Threats and Possible Therapeutic Approaches

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