1995
DOI: 10.1002/hed.2880170107
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Low‐dose radiotherapy for multicystic benign lymphoepithelial lesions of the parotid gland in HIV‐positive patients: Long‐term results

Abstract: Very low-dose radiation (8-10 Gy) provides reliable but temporary cosmetic palliation for BLL. Retreatment was unsatisfactory, and we are now investigating higher initial doses of radiation to prolong palliation and eliminate recurrences.

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Cited by 34 publications
(34 citation statements)
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“…Unfortunately, the duration of the response after low-dose radiotherapy is usually not very long and a second course of radiation is rarely effective. Beitler et al [1] treated 15 patients with high-dose radiotherapy (18-24 Gy delivered in 1.5 Gy daily fractions) and compared them with a former study population that received low-dose radiotherapy (10 Gy, in 2 Gy daily fractions). The follow-up of these 15 patients was more than 2 years.…”
Section: Discussionmentioning
confidence: 99%
“…Unfortunately, the duration of the response after low-dose radiotherapy is usually not very long and a second course of radiation is rarely effective. Beitler et al [1] treated 15 patients with high-dose radiotherapy (18-24 Gy delivered in 1.5 Gy daily fractions) and compared them with a former study population that received low-dose radiotherapy (10 Gy, in 2 Gy daily fractions). The follow-up of these 15 patients was more than 2 years.…”
Section: Discussionmentioning
confidence: 99%
“…BLEC has two hypothesized etiologic mechanisms. The first theorized pathogenesis of BLEC is the “obstructive theory” which states that lymphoid proliferation in the parotid gland leads to ductal obstruction and salivary dilation that mimics a true cyst 1,3,4,79. The second hypothesized theory is that HIV-related reactive lymphoproliferation occurs in the lymph nodes of the parotid gland.…”
Section: Literature Reviewmentioning
confidence: 99%
“…Fine-needle aspiration biopsy of BLEC results in clear, proteinaceous (straw-colored) fluid, with a mixture of epithelial (squamous) and benign lymphoid cells 7,10. This combination of history, physical examination, and fine-needle aspiration biopsy is diagnostic for BLEC 3,10…”
Section: Literature Reviewmentioning
confidence: 99%
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“…Very low dose radiation can provide reliable but temporary palliation in parotid disease. 2 The diagnosis should be based on cytologic findings, in the context of consistent clinical and radiologic data and, whenever possible, supported by complementary methods. This case had unique features and probably represented an AIDS-related lesion and distinct entity.…”
Section: A B Acta Cytologicamentioning
confidence: 99%