Low-Power HeNe Laser Treatment of Venous Leg Ulcers

Lundeberg, Thomas; Malm, Mats

doi:10.1097/00000637-199112000-00004

Cited by 89 publications

(51 citation statements)

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“…There were no significant differences in either the proportion of healed ulcers or in the ulcer area in the active LLLT group compared with the placebo group. 53 However, in a parallel study conducted elsewhere at the same time, 12 patients with chronic venous leg ulcers unresponsive to conservative measures showed very positive effects to a course of LLLT over 12 weeks. 54 In the latter study, two ulcers healed completely and there was a 27 per cent reduction in the size of the remaining ulcers.…”

Section: Wound Healingmentioning

confidence: 97%

The current status of low level laser therapy in dentistry, Part 1. Soft tissue applications

Walsh

1997

Australian Dental Journal

271

177

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Despite more than 30 years of experience with low level laser therapy (LLLT) or 'biostimulation' in dentistry, concerns remain as to its effectiveness as a treatment modality. Controlled clinical studies have demonstrated that while LLLT is effective for some specific applications, it is not a panacea. This paper provides an outline of the biological basis of LLLT and summarizes the findings of controlled clinical studies of the use of LLLT for specific soft tissue applications in dentistry. Areas of controversy where there is a pressing need for further research are identified.

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Section: Wound Healingmentioning

confidence: 97%

The current status of low level laser therapy in dentistry, Part 1. Soft tissue applications

Walsh

1997

Australian Dental Journal

271

177

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“…There are numerous reports on the positive effects of various lasers in Refs., 82,83 but there are also several reports with negative or no effects. 84 While a similar device and dosimetry were apparently used, lack of details on precise parameters makes it difficult to interpret these negative results. 85,86 This emphasizes the need to further understand PBM mechanisms that will aid in optimizing effective clinical protocols.…”

Section: Secondary Phasementioning

confidence: 99%

Biophysical Approaches for Oral Wound Healing: Emphasis on Photobiomodulation

Khan

Arany

2015

Advances in Wound Care

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“…Although there is considerable anecdotal support for light treatment of wounds, amongst the several controlled trials only a few small studies have demonstrated benefit [1][2][3][4][5][6][7][8][9][10][11]. There are many factors involved in delayed wound healing: infection is a key element [12].…”

Section: Introductionmentioning

confidence: 99%

Effects of low intensity laser irradiation during healing of infected skin wounds in the rat

Nussbaum

Heras

Pritzker

et al. 2014

Photonics &Amp; Lasers in Medicine

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Background and objective-Low intensity laser irradiation remains a controversial treatment for non-healing wounds. This study examines the effect of low intensity light on healing of infected skin wounds in the rat.Materials and methods-Wounds on the rat dorsum were inoculated with Pseudomonas aeruginosa. Wounds were irradiated or sham-irradiated three times weekly from day 1 to 19 using 635-nm or 808-nm diode lasers delivering continuous wave (CW) or intensity modulated (3800 Hz) laser radiation, all at radiant exposures of 1 and 20 J/cm 2 . Wound area and bacterial growth on the wound surface were evaluated three times a week. Histological and immunohistochemical analyses were performed at day 8 and 19.Results-Wounds that were irradiated using a wavelength of 635 nm (1 and 20 J/cm 2 ) or intensity modulated 808-nm laser light at 20 J/cm 2 were smaller in area at day 19 than the shamirradiated controls (achieved significance level=0.0105-0.0208) and were similar to controls in respect of bacterial growth. The remaining light protocols had no effect on wound area at day 19 although they increased Staphylococcus aureus growth across the time line compared with controls (p<0.0001 to p<0.004). CW 808-nm light at 20 J/cm 2 significantly delayed half-heal time.Histological and immunohistochemical analyses supported wound closure findings: improved

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Low-Power HeNe Laser Treatment of Venous Leg Ulcers

Cited by 89 publications

References 0 publications

The current status of low level laser therapy in dentistry, Part 1. Soft tissue applications

The current status of low level laser therapy in dentistry, Part 1. Soft tissue applications

Biophysical Approaches for Oral Wound Healing: Emphasis on Photobiomodulation

Effects of low intensity laser irradiation during healing of infected skin wounds in the rat

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