2019
DOI: 10.5582/bst.2019.01247
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<i>PRKCH</i> polymorphism is associated with rheumatoid arthritis in a Chinese population

Abstract: Genetic factors have been widely considered to have a substantial effect on the susceptibility to rheumatoid arthritis (RA). The purpose of this study was to determine whether the four newly discovered polymorphisms in a genome-wide association study (GWAS) meta-analysis confer susceptibility to RA in a Chinese Han population. We conducted a case-control study involving 359 RA cases and 873 age-and gender-matched controls and performed genotyping of four single nucleotide polymorphisms (SNPs), rs227163, rs7262… Show more

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