2020
DOI: 10.2147/idr.s260359
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<p>Antimicrobial Resistance and Genotyping of Bacteria Isolated from Urinary Tract Infection in Children in an Iranian Referral Hospital</p>

Abstract: Introduction: Urinary tract infection (UTI) is one of the most common bacterial infections in childhood, and the increasing rate of antibiotic resistance to the commonly prescribed antimicrobial agents against it has become a major concern. The aim of this study was to determine the antibiotic resistance and genotyping of bacteria isolated from urine cultures in patients referred to the Children's Medical Center, Tehran, Iran. Methods: During the 1-year period, antimicrobial susceptibility profiles of strains … Show more

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Cited by 8 publications
(10 citation statements)
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“…In addition to blood samples in the present study, Burkholderia cepacia isolates were also detected in urine (23.62%) indicating the occurrence of the pathogens as ethiological agents for urinary tract infections. Burkholderia cepacia is one of the Gram negative uropathogenic bacteria causing urinary tract infections (UTI) after Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa ( 19 ).…”
Section: Discussionmentioning
confidence: 99%
“…In addition to blood samples in the present study, Burkholderia cepacia isolates were also detected in urine (23.62%) indicating the occurrence of the pathogens as ethiological agents for urinary tract infections. Burkholderia cepacia is one of the Gram negative uropathogenic bacteria causing urinary tract infections (UTI) after Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa ( 19 ).…”
Section: Discussionmentioning
confidence: 99%
“…pneumoniae, and P. aeruginosa to be major pathogens [21][22][23] . These discrepancies in study ndings may be attributed to regional variations, differences in environmental factors, and variations in population demographics.…”
Section: Discussionmentioning
confidence: 99%
“…A clear understanding of UTI symptoms and treatment approaches is crucial for appropriate antibiotic choice, preventing severe complications and antibiotic misuse, and inhibiting the development of antibiotic-resistant bacteria [ 6 ]. The most common pathogen isolated from urine cultures is Escherichia coli , 80–90% [ 7 ]. However, other bacteria that were rarely isolated previously are now rising (Proteus , Citrobacter , Enterobacter , and Serratia species) [ 8 ].…”
Section: Introductionmentioning
confidence: 99%
“…Despite increased antibiotic resistance, beta-lactam antibiotics and TMP-SMX remain first-choice treatments for pediatric UTIs [ 8 ]. Patients diagnosed with UTI are administered empirical antimicrobial treatment until the etiological agent is determined, which may further increase antibiotic resistance [ 7 ]. Our study aimed to determine the antimicrobial susceptibility patterns of pediatric UTI-causing pathogens, including ESBL-producing bacteria, in Saudi Arabia.…”
Section: Introductionmentioning
confidence: 99%