<p>Association Between Urinary Tract Infection in the First Trimester and Risk of Preeclampsia: A Case–Control Study</p>

Abstract

Background: Urinary tract infection (UTI) is a common clinical problem during pregnancy that can have serious consequences for the mother and fetus. Some studies have suggested that UTI can trigger or aggravate preeclampsia. The present study aimed to investigate the association between urinary tract infection in the first trimester and the risk of preeclampsia in pregnant women referring to Bahar hospital of Shahroud. Patients and Methods: In this case-control study, 92 pregnant women with a diagnosis of preeclampsia were selected as cases, and for comparison 92 pregnant women were selected as control. History of previous UTI in the first trimester was assessed as a risk factor. Data were analyzed using SPSS 16 software and related statistical tests such as mean and standard deviation, chi-square, and independent t-test. Results: In this study, the mean age of the patients was 28.6 ± 6.9 years that no significant differences were found between the two groups. It was also found that 37 (40.2%) patients in the case group and 29 (31.5%) patients in the control group had a UTI which was significantly (p<0.043) higher in the case group. Also, in the multivariate regression model, UTI was significantly associated with preeclampsia (p<0.048), so that UTI increases the risk of preeclampsia (OR=1.86). Conclusion: The results of this study showed UTI during the first trimester of pregnancy is associated with the risk of preeclampsia. Therefore, controlling and treatment of urinary infections can reduce the risk of preeclampsia in the later months.

Urinary Tract Infection in Pregnancy and Its Effects on Maternal and Perinatal Outcome: A Retrospective Study

“…Urinary tract infections (UTI) continue to be one of the most common medical conditions complicating pregnancy, with a prevalence of approximately 20% [1]. A UTI is diagnosed when there is an overgrowth of bacteria in the urinary tract (≥105 counts/mL of urine), irrespective of the presence of clinical symptoms [2]. UTI include a spectrum of disorders, ranging from those affecting the lower urinary tract, like asymptomatic bacteriuria (ASB) and cystitis, to those affecting the kidney, such as pyelonephritis.…”

Urinary Infections in a Hospital Unit in Central Portugal – 5-Year Analysis

“…3% of the women in the sample under analysis were pregnant. The risk of pre-eclampsia increases in pregnant women who develop a urinary tract infection during the first trimester, and in our study 17,5% of pregnant women were in the first trimester [21] and special attention should therefore be given to these women. In the study under analysis here, it was detected that it is in the third trimester that more pregnant women developed urinary infections, as opposed to the literature that points to the first trimester as more prevalent [22].…”

Procalcitonin levels differences in preeclampsia and non preeclampsia

“…Other studies have also reported that pregnant women who experience urinary tract infections have a high risk of preeclampsia (Easter et al, 2016). Research conducted in Iran also reported that the first-trimester pregnancy accompanied by urinary tract infections is closely related to the incidence of preeclampsia (Zahedkalaei et al, 2020). Therefore, early treatment and prevention of urinary tract infections in pregnant women are expected to reduce the possibility of preeclampsia.…”