&lt;p&gt;Classical Dermatomyositis: A Case Report&lt;/p&gt;

Pokhrel, Sushant; Pardhe, Bashu Dev; Giri, Nisha; Pokhrel, Rakesh; Paudel, Deliya

doi:10.2147/ccid.s234452

Cited by 10 publications

(6 citation statements)

References 15 publications

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“…Dermatomyositis is associated with high degree of malignancy particularly ovarian, lung, pancreatic, stomach and colorectal. 5 The patient showed typical features for diagnosis of dermatomyositis such as progressive symmetrical muscle weakness, elevated muscle enzyme and erythematous rashes all over the body with positive anti-Mi-2 antibody, which is suggests dermatomyositis. Mi-2 antigen, nuclear helicase protein, forms part of the nucleosome remodeling deacetylase (NuRD) complex involved in transcription regulation.…”

Section: Discussionmentioning

confidence: 85%

An interesting case of dermatomyositis with classical presentation

et al. 2022

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Dermatomyositis, a connective tissue disorder, is an idiopathic inflammatory myopathy characterised by skin manifestation. The diagnosis of dermatomyositis is based on rashes on the skin, progressive muscle weakness, elevated serum muscle enzymes, abnormal electromyogram, and abnormal findings on muscle biopsy. Hereby presenting this rare case of a 57-year-old female with dermatomyositis with all the typical clinical findings with interstitial lung disease.

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Section: Discussionmentioning

confidence: 85%

An interesting case of dermatomyositis with classical presentation

et al. 2022

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“…Dermatomyositis is classified into classical dermatomyositis, amyopathic dermatomyositis, juvenile dermatomyositis, hypomyopathic dermatomyositis, clinically amyopathic dermatomyositis, and clinically amyopathic, evolving into classic dermatomyositis [5]. While most cases of dermatomyositis involve both muscle and skin symptoms, there are variations.…”

Section: Discussionmentioning

confidence: 99%

Beyond the Rash: Exploring the Symptoms and Diagnosis of Dermatomyositis

Patel,

Parekh

et al. 2023

Cureus

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Dermatomyositis represents a rare autoimmune disorder characterized by the concurrent presentation of inflammatory myopathy and distinctive cutaneous manifestations. Herein, we present a comprehensive case report involving a 62-year-old male patient exhibiting a complex array of symptoms encompassing progressive muscle weakness, characteristic dermatological findings, and systemic involvement. This case report serves to illuminate the diagnostic intricacies inherent to dermatomyositis and underscore the imperative for a multidisciplinary approach to its effective management.The clinical presentation of the patient featured hallmark signs such as the classic heliotrope rash, Gottron's papules, and proximal muscle weakness, all indicative of dermatomyositis. Laboratory investigations revealed elevated muscle enzyme levels and the presence of positive autoantibodies, thereby reinforcing the diagnostic framework. Imaging modalities substantiated muscular involvement, while electromyography provided definitive evidence of myopathic alterations. Notably, a muscle biopsy further corroborated the diagnostic findings. In response to these diagnostic cues, the patient was expeditiously initiated on a therapeutic regimen encompassing corticosteroids, immunosuppressants, calcium channel blockers, and a tailored physical therapy program. This case underscores the pivotal significance of timely recognition and intervention for the treatment of dermatomyositis, thus mitigating the risk of long-term complications and enhancing the patient's overall quality of life. Moreover, it highlights the indispensability of interdisciplinary collaboration, uniting the expertise of dermatologists, rheumatologists, and neurologists, in navigating the intricacies of this intricate autoimmune disorder. We emphasize the pressing need for a comprehensive evaluation and an individualized therapeutic approach, thereby amplifying the prospects for superior patient outcomes and an improved quality of life.

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“…Apart from topical ointment use as per her dermatologist, there was no drug use. 1,2 On general physical examination, her vitals were within normal limits. There was facial puffiness along with maculopapular erythematous rash present over forehead, nose, cheek, arms, and knuckles.…”

Section: Case Reportmentioning

confidence: 99%

A typical case of Dermatomyositis

Mandal,

Sarkar,

Praharaj

et al. 2024

JDC

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Dermatomyositis, a connective tissue disorder, is an idiopathic inflammatory myopathy characterized by skin manifestation. The diagnosis of dermatomyositis is based on characteristic skin rash, progressive muscle weakness, elevated serum muscle enzymes, abnormal EMG and muscle biopsy findings. Here we present an atypical case of a 68year old lady with all typical clinical findings failed to show response despite proper stepwise management.

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<p>Classical Dermatomyositis: A Case Report</p>

Cited by 10 publications

References 15 publications

An interesting case of dermatomyositis with classical presentation

An interesting case of dermatomyositis with classical presentation

Beyond the Rash: Exploring the Symptoms and Diagnosis of Dermatomyositis

A typical case of Dermatomyositis

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