2020
DOI: 10.2147/ceg.s234698
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<p>Effect of Ginger Powder Supplementation in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Clinical Trial</p>

Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders. The main causes of NAFLD are associated with insulin resistance, severe lipid metabolism disorders, oxidative stress and inflammation. Previous studies have reported that ginger has positive metabolic results. Aim: The aim of this study was to determine the effect of ginger powder supplement on lipid profiles, insulin resistance, liver enzymes, inflammatory cytokines and antioxidant status in patients with … Show more

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Cited by 38 publications
(75 citation statements)
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“…The duration of ginger consumption varied from four to 12 weeks. Of the 12 studies, four included participants with type 2 diabetes (Azimi et al., 2014; Gholinezhad et al., 2020; Javid et al., 2019; Shidfar et al., 2015), two included participants with final stage renal disease and peritoneal dialysis (Imani et al., 2015; Seddik, 2015), one included participants with cancer (Danwilai et al., 2017), one included obese participants (Attari et al., 2015), one included participants with ulcerative colitis (Nikkhah‐Bodaghi et al., 2019), one included subjects with non‐alcoholic fatty liver disease (Rafie et al., 2020), one included knee osteoarthritis patients (Naderi et al., 2016), and one included adults with tuberculosis (Kulkarni & Deshpande, 2016).…”
Section: Resultsmentioning
confidence: 99%
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“…The duration of ginger consumption varied from four to 12 weeks. Of the 12 studies, four included participants with type 2 diabetes (Azimi et al., 2014; Gholinezhad et al., 2020; Javid et al., 2019; Shidfar et al., 2015), two included participants with final stage renal disease and peritoneal dialysis (Imani et al., 2015; Seddik, 2015), one included participants with cancer (Danwilai et al., 2017), one included obese participants (Attari et al., 2015), one included participants with ulcerative colitis (Nikkhah‐Bodaghi et al., 2019), one included subjects with non‐alcoholic fatty liver disease (Rafie et al., 2020), one included knee osteoarthritis patients (Naderi et al., 2016), and one included adults with tuberculosis (Kulkarni & Deshpande, 2016).…”
Section: Resultsmentioning
confidence: 99%
“…Our meta‐analysis also showed that ginger supplementation significantly increases TAC levels (five studies) (SMD: 0.40; 95% CI: 0.06, 0.73; I 2 = 42.8%) (Figure 5). Four studies (Attia et al., 2013; Gholinezhad et al., 2020; Nikkhah‐Bodaghi et al., 2019; Rafie et al., 2020) have shown that ginger intake non‐significantly increases TAC. One study showed that ginger intake increases TAC significantly (Shidfar et al., 2015).…”
Section: Resultsmentioning
confidence: 99%
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“…A 3-month study in 46 people with NAFLD found that taking powdered ginger significantly reduced ALT, TC, LDL–C, blood glucose levels, HOMA (Homeostatic Model Assessment), C-reactive protein, compared to taking a placebo [ 39 ]. Similar results were presented in another study involving 44 NAFLD patients.…”
Section: Herbal and Dietary Productsmentioning
confidence: 99%