LXVI Fate of Implants in Rats

Hohmann, Albert; Hilger, Jerome A.; Carley, Richard

doi:10.1177/000348946407300317

Cited by 11 publications

(2 citation statements)

References 6 publications

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“…There are no tissue changes other than further fibrosis and capsule formation. Additionally, animal experiments by Homan et a1 [4] have suggested that the use of Teflon in the particulate form is safe as compared with the solid form. Its high viscosity is considered to be an advantage in slowing its absorption and maximizing its effective time in situ in the vocal cord.…”

Section: Discussionmentioning

confidence: 99%

Glycerine injection and crystal formation in the larynx: A negative study

Klabacha

Farag

Reyes

et al. 1981

Journal of Surgical Oncology

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Glycerine as a vehicle may be injected alone or with Teflon to reposition a lateral lying paralyzed vocal cord. During the study of a particular patient, crystal formation was observed in laryngeal tissues injected with glycerine. It was hypothesized that glycerine metabolized to oxalic acid crystals via the glyoxylic acid pathway. To confirm this proposition, the gluteus muscle of guinea pigs was injected with glycerine, and at weekly intervals submitted for ordinary and polarized light microscopic examination. The formation of crystals after glycerine injection was not found in the guinea pig. Similarly, no foreign material or crystals were found after centrifuging the stored glycerine.

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Section: Discussionmentioning

confidence: 99%

Glycerine injection and crystal formation in the larynx: A negative study

Klabacha

Farag

Reyes

et al. 1981

Journal of Surgical Oncology

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show abstract

“…Investigations have been largely confined to surgical-anatomical studies,1-3 and to the determination of the surgical risk.4-7 The fate and tissue tolerability of various materials used for stapedial substitution were made the subject of further studies. [8][9][10][11] However, comparatively few efforts have been made toward the assessment of the purely physical factors involved in stapedial replacement.12 The results of these latter studies, in the opinion of the present writers, have not been really conclusive.…”

mentioning

confidence: 94%