Lymphoepithelial Carcinoma of the Minor Salivary Gland

Primary lymphoepithelioma-like carcinoma of minor salivary gland: A case report with immunohistochemical and in situ hybridization studies

“…Nevertheless, the presentation of primary LEC affecting the minor salivary gland was hitherto never described in Asians, except for one previous case derived from the same buccal area of an elderly white woman in the Englishlanguage literature. 1 As for malignancies of intraoral minor salivary glands, the most common histologic type is mucoepidermoid carcinoma followed by adenoid cystic carcinoma and adenocarcinoma, not otherwise specified, etc. 6 Therefore, this case represents an extremely rare type of carcinoma of the minor salivary glands.…”

“…1 It was associated with concurrent BLE and neck lymph metastasis at initial diagnosis. In this report, we describe the second LEC of the minor salivary gland that occurred in an Asian patient without associated BLE in conjunction with immunohistochemical and EBV studies.…”

Fine Needle Aspiration in a Malignant Lymphoepithelial Lesion

“…In the Asian population, however, the incidence of tumors arising in the submandibular gland is higher, reaching 50% of cases. [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Table II.…”

“…They also reported finding strong evidence of EBV infection in the pathogenesis of these tumors. [1][2][3][4][5][6][7][8][9][10] Kanjanavirojkul, Kularbkaew and Yutanawiboonchai 14 Chinese Parotid gland 9 Nagao et al, 1983 15 Japanese Parotid gland 2 Amaral and Nascimento, 1984 16 Submandibular gland 1 Kott et al, 1984 17 Hispanic (1) Parotid gland 3 Filipino (1) American (1) Yazdi and Hogg, 1984 18 Inuit Submandibular gland 1 Cheng, 1986 19 Chinese Parotid gland 3 Kitazawa et al, 1987 20 Japanese Parotid gland 1 Autio-Harmainen et al, 1988 21 Norwegian Parotid gland 1 Chomette et al, 1992 22 French Submandibular gland 1 Chan et al, 1994 4 Chinese Parotid gland 5 Gunhan et al, 1994 23 Turkish Parotid gland 2 Christansen et al, 1995 5 Canadian Parotid gland 1 Kountakis et al, 1995 24 Hispanic Parotid gland 1 Leung et al, 1995 7 Chinese Parotid gland (8) 10 Submandiublar gland (2) Abdulla and Mian, 1996 1 Arab Parotid gland 1 Jang et al, 1997 6 Korean Submandibular gland 1 Worley and Daroca, 1997 25 American Minor salivary gland 1 Squillaci et al, 2000 9 Italian Parotid gland 1 Wu et al, 2001 10 Italian Hanji and Gohao 14 reported on the prognosis of MLEL. A total of 45 cases were followed from 8 months to 12 years: 10 patients survived for more than 5 years; 1 of 9 patients with regional lymph nodes metastases was alive 12 1 /2 years after surgery; 36 of 47 patients had lymph node metastases; and 1 patient who had metastatic lung nodules was alive 5 years after local excision.…”

Einseitiger schmerzloser Exophthalmus

“…In den großen und kleinen Speicheldrüsen wurden diese seltenen Tumoren vereinzelt bei Eskimos, Grönländern und im südchinesischen Raum beschrieben [2,3,5].Wir berichten über den ersten Fall eines lymphoepitheliomartigen Karzinoms der Tränendrüse. Eine Metastasierung aus dem Nasopharynx in die Tränendrüse wurde endoskopisch und bioptisch ausgeschlossen.…”