Macromol. Biosci. 4/2013

Nanostructured Multilayer Films Assembled from Poly(dopamine)‐Coated Carbon Nanotubes for Controlling Cell Behavior

“…The multilayer film consisted of nanoscale interpenetrated networks of a dense entanglement of CNTs. PLL reacted with PDA and gave rise to interlayer cross‐linking through Schiff base formation and Michael addition reaction at room temperature . Compared with the multilayer films, the PDA surfaces had no clear nanoscaled fibrous texture (Figure (d)).…”

“…Aggregation of CNTs in aqueous solution reduced the absorption peak intensity. This linear increase of UV/Vis absorbance from PDA, CNTs to CNTs@PDA could also be found in previous work …”

Multifunctional MgF2/Polydopamine Coating on Mg Alloy for Vascular Stent Application

“…As a simple, versatile, and effective strategy to promote cell adhesion onto substrates with various material type and shape under solvent-free and non-toxic condition, polydopamine (PDA) films has attracted much attention in the field of biomaterials surface modification since Lee et al reported it in 2007 [41] . In the field of vascular biomaterials, PDA coating has been used as an immobilization layer for vascular endothelial growth factor (VEGF) [42,43] , heparin [44,45] , etc., and has also been used to control cell behaviors directly on the surface, which demonstrated that human umbilical vein endothelial cells (HUVECs) could adhere well and spread with a high viability on PDA coating [46][47][48] ; moreover, it showed that PDA coating on 316L stainless steel stent decreased adhesion and proliferation [48] .…”

“…While in this study, EA. [47] ; on the other hand, it could facilitate the secretion, deposition and assembly of endogenous fibronectin (Fn), resulting in the formation of Fn fibril colocalizing with α 5 β 1 integrin, which plays a key role in the adhesion of HUVECs on PDA [46] . As to the effect of PDA coating on vascular smooth muscle cells (VSMCs) [48] , inhibition of VSMCs' adhesion and proliferation was demonstrated compared to the 316L stainless steel control.…”

Facile Cell Sheet Harvest and Translocation Mediated by a Thermally Expandable Hydrogel with Controlled Cell Adhesion

“…[17] Prolonged incubation of biomaterials within PD leads to the deposition of greater amounts of PD, and enhanced cell adhesion likely in a PD-concentration-dependent manner. [23,24] However, the harvest and translocation of the cell sheet requires a balance between cell attachment and detachment. Thus, a general single-step coating process may not be proper because the excessive deposition of PD allows for cell adhesion, but prevents cell detachment.…”