Magnetic porous organic polymers for extraction of cardiovascular drugs in human urine samples followed by HPLC-UV

Abstract

Prepared magnetic porous organic polymers show high extraction efficiency towards cardiovascular drugs.

Green electrochemical nanosensor platform design for mexiletine detection based on Citrus reticulata peel-mediated iron nanoparticles and quantum dots and investigation of the adsorption mechanism by the DFT-D3 method

“…26 Mexiletine (MXL) is a class IB antiarrhythmic drug with a narrow therapeutic range, used for treating life-threatening ventricular tachyarrhythmias, especially after myocardial infarction. 27,28 In the literature, for the determination of MXL in drugs and biological samples, such as serum, urine and plasma, the electrochemical method, 29 high-performance liquid chromatography (HPLC), 30,31 HPLC with UV detection, 32,33 HPLC with fluorescence detection, 34,35 gas chromatography (GC) coupled with solid-based dispersive liquid-liquid microextraction, 36 different derivatization reagents in HPLC, 37 liquid chromatography with mass spectrometry (LC-MS), 38 GC-MS, 39 and capillary GC-MS 40 have been used.…”

Core‐shell magnetic porous organic polymer for magnetic solid‐phase extraction of fluoroquinolone antibiotics in honey samples followed by high‐performance liquid chromatography with fluorescence detection

“…Magnetic porous triazinyl covalent organic polymer with high porous structure and good magnetism was used as adsorbent for MSPE‐HPLC‐MS analysis of carbamate pesticides in lemon and grape juice. In our previous work [23], a kind of MOPs was synthesized using benzidine and resorcinol as building units by a mild azo reaction. This magnetic material had good extraction performance for cardiovascular drugs with fast adsorption and desorption kinetics, high EFs, and good anti‐matrix interference ability.…”