Magnetically responsive composites: electron beam assisted magnetic nanoparticle arrest in gelatin hydrogels for bioactuation

Deuflhard, Marie; Eberbeck, Dietmar; Hietschold, Philine; Wilharm, Nils; Mühlberger, Marina; Friedrich, Ralf P.; Mayr, Stefan

doi:10.1039/c9cp02910a

Cited by 21 publications

(14 citation statements)

References 31 publications

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“…A similar quasi-equilibrium transformation of a ferrofluid into a solid substance by means of carrier liquid polymerization has been carried out during the synthesis of magnetoactive composites in the works. [18][19][20][21] The ferrofluid, polymerized in the presence of an external field, forms a texture, the anisotropy degree of which depends on the polymerization field, the polymerization temperature and the intensity of the interparticle dipole-dipole interactions. Next, we will analyze the structure of the resulting ferrocomposite depending on the parameters α p , σ p , and λ p , at which the polymerization process takes place.…”

Section: Modelmentioning

confidence: 99%

“…[12][13][14][15][16][17] One of the methods for preparing magnetoactive ferrocomposites is based on the polymerization of ferrofluids. [18][19][20][21] The latter are a stable colloidal suspension of single-domain magnetic nanoparticles with a diameter of ∼10 nm in non-magnetic liquid carriers. 22 In a liquid matrix, magnetic nanoparticles perform Brownian motion.…”

Section: Introductionmentioning

confidence: 99%

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Structure and magnetization of a magnetoactive ferrocomposite

2022

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Section: Modelmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Structure and magnetization of a magnetoactive ferrocomposite

2022

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“…Deuflhard et al embedded iron oxide nanoparticles in gelatin 3D networks by electron beam radiation [ 52 ]. The magnetic field-responsive hydrogels were linked to radiation dose, gel concentration, and so on.…”

Section: Classification Of Smart Hydrogelsmentioning

confidence: 99%

“… Schematic illustration of reversible bending of an iron gel: ( a , b ) show the bending degree of field off and on, respectively [ 52 ]. …”

Section: Figurementioning

confidence: 99%

Recent Advances in Smart Hydrogels Prepared by Ionizing Radiation Technology for Biomedical Applications

et al. 2022

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Materials with excellent biocompatibility and targeting can be widely used in the biomedical field. Hydrogels are an excellent biomedical material, which are similar to living tissue and cannot affect the metabolic process of living organisms. Moreover, the three-dimensional network structure of hydrogel is conducive to the storage and slow release of drugs. Compared to the traditional hydrogel preparation technologies, ionizing radiation technology has high efficiency, is green, and has environmental protection. This technology can easily adjust mechanical properties, swelling, and so on. This review provides a classification of hydrogels and different preparation methods and highlights the advantages of ionizing radiation technology in smart hydrogels used for biomedical applications.

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“…In bioengineering, FGs have been extensively studied as responsive working bodies in various detectors and actuators that provide transfer of a mechanical force under remote control of a magnetic field [ 16 , 17 , 18 , 19 , 20 ]. In addition, spherical FG microparticles can be used for magnetic biosensing and for drug delivery purposes, in which the force associated with each particle as compared with the forces associated with corresponding biochemical bonds are also very important [ 4 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Mechanical Force Acting on Ferrogel in a Non-Uniform Magnetic Field: Measurements and Modeling

et al. 2022

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The development of magnetoactive microsystems for targeted drug delivery, magnetic biodetection, and replacement therapy is an important task of present day biomedical research. In this work, we experimentally studied the mechanical force acting in cylindrical ferrogel samples due to the application of a non-uniform magnetic field. A commercial microsystem is not available for this type of experimental study. Therefore, the original experimental setup for measuring the mechanical force on ferrogel in a non-uniform magnetic field was designed, calibrated, and tested. An external magnetic field was provided by an electromagnet. The maximum intensity at the surface of the electromagnet was 39.8 kA/m and it linearly decreased within 10 mm distance from the magnet. The Ferrogel samples were based on a double networking polymeric structure which included a chemical network of polyacrylamide and a physical network of natural polysaccharide guar. Magnetite particles, 0.25 micron in diameter, were embedded in the hydrogel structure, up to 24% by weight. The forces of attraction between an electromagnet and cylindrical ferrogel samples, 9 mm in height and 13 mm in diameter, increased with field intensity and the concentration of magnetic particles, and varied within 0.1–30 mN. The model provided a fair evaluation of the mechanical forces that emerged in ferrogel samples placed in a non-uniform magnetic field and proved to be useful for predicting the deformation of ferrogels in practical bioengineering applications.

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Magnetically responsive composites: electron beam assisted magnetic nanoparticle arrest in gelatin hydrogels for bioactuation

Abstract: Tailored ferrogel bioactuators are feasible by arresting nanoparticles in simple gelatin gels with the help of electron beam treatment.

Cited by 21 publications

References 31 publications

Structure and magnetization of a magnetoactive ferrocomposite

Structure and magnetization of a magnetoactive ferrocomposite

Recent Advances in Smart Hydrogels Prepared by Ionizing Radiation Technology for Biomedical Applications

Mechanical Force Acting on Ferrogel in a Non-Uniform Magnetic Field: Measurements and Modeling

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