Malignant glomus tumor of the gastric antrum with hepatic metastases: a case report and literature review

<p>Lesser Sac Glomangiosarcoma With Simultaneous Liver And Lymph Nodes Metastases Mimicking Small Bowel Gastrointestinal Stromal Tumor; Immunohistochemistry And Empirical Chemotherapy</p>

“…As it is mentioned above glomus tumors are usually benign but malignancy incidence in these tumors either represents clinically metastasis malignancy or simply histopathologically malignant. No specific pattern is recognized for metastasis of malignant glomus tumor and metastasis via both the lymphatic system and blood is reported in the literature 1–3. The present report is the first report of an exophytic gastric glomangiosarcoma with simultaneous liver and lymph nodes metastases that can help to recognize different features of this type of tumor.…”

“…A 3-cm mass in a sixty-five-year-old woman with metastasis to the brain and kidney was another case published by Song et al in 2010 8. The next published case was introduced in 2018 by Bodolan et al In this case, the patient was an eighty-year-old woman with a mass sized 7.1 cm and liver metastasis 1. And the last published case was a seventy-two-year-old male with a mass sized 6 cm that was introduced by Toti et al’s in 2019 9.…”

“…Malignant glomus tumors are categorized into two groups. First, tumors that are malignant from the very beginning (de novo) and second, tumors that are created through malignancy transformation in benign tumors 1. In 2001, Folpe et al defined three criteria for the identification of malignant and benign glomus tumors.…”

“…Although glomus tumors are basically benign tumors with a good prognosis, low recurrence, low local invasion and rarely with metastasis, they could be potentially very malignant and they can lead to the death of the patient after causing widespread metastasis 1. In the gastrointestinal tract, the stomach is the prevalent place for glomus tumors; however, there are only seven cases of malignant glomus tumors with metastasis in the stomach reported in the literature (Table 1).…”

“…In the gastrointestinal tract, the stomach is the prevalent place for glomus tumors; however, there are only seven cases of malignant glomus tumors with metastasis in the stomach reported in the literature (Table 1). 1,4–9 The first case was reported in 2001 by Folpe et al in which the patient was a sixty-nine-year-old man with a 9.5-cm mass and liver metastasis 4. In 2002, Miettinen et al reported another patient who was also 69 years old with a 6.5-cm mass and liver metastasis 5.…”