Malignant neoplasms metastatic to gingivae

Adenocarcinoma of the rectum metastatic to the oral cavity. Two cases and a review of the literature

“…Five percent originated in the As of 1974, Perlmutter and others found 19 cases in the literature involving gingiva alone.4 Of the ten cases reported by Ellis and coworkers, maxillary gingiva was involved in four, mandibular gingiva in four, and both in two. 8 Metastatic lesions of the oral cavity may clinically mimic benign lesions such as fibroma, giant cell granuloma, pyogenic granuloma or periodontal abscess: as in our two cases. Moffat recently reported on an edentulous patient with a moderately well-differentiated rectal carcinoma presenting as an ulcerative epulis of the lower alveol~s.~ In those with bony involvement of the jaw, only 5% to 20% involve the maxilla, and the rest reside in the As in our first case, the third molar area is the most common site within the mandible.''…”

Metastasis of renal clear-cell carcinoma to the oral mucosa, an atypical location

“…In the case of metastatic tumors for which the primary tumor is unknown, we advocate performing a Pet-scan if the results of the Body-Scan are negative. The treatment will depend on many factors; however in cases of metastasis to soft tissue, complete excision is advisable regardless of the degree of dissemination (1)(2)(3)(4)(5)(6)(7)(8)(9)(10). If it involves the bone and is the only location where it is seated, surgical resection is advised if possible, but if the extension study reveals evidence of the spread of the primary tumor or that the metastasis cannot be resected, palliative treatment is recommended.…”

Pulmonary adenocarcinoma metastatic to the gingiva

“…Usually, gingival or oral mucosal metastases extend from mandibular or maxillary lesions, and spread beyond the periosteum to cause visible gingival or oral mucosal masses. Ellis et al 5 suggested that direct extension into the gingiva from underlying bone was not possible. They emphasized the following criteria: surgical or radiographic evidence that bone underlying the metastasis was not involved, confinement of the metastatic lesion to the gingiva and adjacent alveolar mucosa, and histologic analysis of the primary tumor and gingival metastases.…”

“…Ellis et al 5 reported a 27-year-old woman with a tumor that developed 15 days after lung resection. In our patient, the gingival swelling appeared on the 14th postoperative day in a similar manner.…”