Malignant schwannoma of the parapharyngeal space in von Recklinghausen's disease: a case report and review of the literature

Abstract

Neurofibromatosis (NF) or von Recklinghausen's disease is frequently accompanied by malignant tumours, which can occur at any site in the body. These malignancies are mainly of soft tissue origin. Of all head and neck malignancies, the number of soft tissue sarcomas is limited and in combination with NF this type of tumour is a rare event. In this report we describe the clinical course of a young female patient with NP, who presented with a massive malignant schwannoma in the parapharyngeal space, and review the pertinent literature.

Malignant peripheral nerve sheath tumors of the head and neck: Management of 10 cases and literature review

“…In survival statistics restricted to head and neck MPNST, analysis revealed 5‐year survival rates between 15% and 47% 1, 6, 11, 13, 16. Table 2 gives an overview of all series and case reports of head and neck MPNSTs published to date, including the treatment modalities used and the outcome achieved 1, 6, 7, 10–13, 15–18, 21, 23–29…”

Plexiform Neurofibroma of the Larynx in Children: About an Unusual Case Report

“…Most authors favor external approaches with alternative airway provisions such as a preliminary tracheotomy in larger tumors. Median or lateral thyrotomy or median or lateral pharyngotomy are recommended [1,[8][9][10][11][12]. In smaller tumors, endoscopic (laser-assisted) resection of the tumor can be a reasonable treatment option [1,13].…”

Pediatric laryngeal schwannoma: Case report and literature review

“…Median or lateral thyrotomy or median or lateral pharyngotomy are recommended. [10] In smaller tumors, endoscopic (laser-assisted) resection of the tumor can be a reasonable treatment option. Independent of the approach, restoration of the vocal cord mobility is possible even if it was immobile prior to surgery.…”