Massive Transfusion

Jutkowitz, L. Ari

doi:10.1016/b978-1-4557-0306-7.00063-5

Cited by 3 publications

(3 citation statements)

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“…Using an estimated blood volume of 90 mL/kg for dogs, the dog in this report was autotransfused approximately 58% of his blood volume in less than 3 hours, thus fitting the criteria for massive transfusion. Massive transfusion and autotransfusion have been associated with coagulopathy, hypocalcemia, and other electrolyte disturbances . Coagulopathy can occur due to dilution of platelets and clotting factors, or secondary to anticoagulants added to the donor blood.…”

Section: Discussionmentioning

confidence: 63%

“…Massive transfusion is defined as the transfusion of blood products in excess of the patient's blood volume in a 24‐hour period or transfusion of half of the patient's blood volume in a 3‐hour period . Using an estimated blood volume of 90 mL/kg for dogs, the dog in this report was autotransfused approximately 58% of his blood volume in less than 3 hours, thus fitting the criteria for massive transfusion. Massive transfusion and autotransfusion have been associated with coagulopathy, hypocalcemia, and other electrolyte disturbances .…”

Section: Discussionmentioning

confidence: 99%

“…Massive transfusion and autotransfusion have been associated with coagulopathy, hypocalcemia, and other electrolyte disturbances. 2,4,13,16 Coagulopathy can occur due to dilution of platelets and clotting factors, or secondary to anticoagulants added to the donor blood. The coagulopathy that developed in this dog was suspected to be due to consumption of clotting factors as evidenced by the clots that formed during the bleeding prior to autotransfusion of a very large volume of blood, resulting in significant dilution of clotting factors and platelets.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Successful management of catastrophic peripheral vascular hemorrhage using massive autotransfusion and damage control surgery in a dog

Ghosal

Bos

2019

J Vet Emergen Crit Care

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Objective To describe a case of massive transfusion using unwashed, non‐anticoagulated, nonsterile autologous blood in a dog with catastrophic hemorrhage from a peripheral vessel during orthopedic surgery. A damage control surgical strategy was also employed. Case Summary A 6‐year‐old, 48 kg neutered male Labrador Retriever experienced massive hemorrhage after transection of a large blood vessel while undergoing femoral head and neck osteotomy. Blood was collected from clean, but not sterile, suction canisters and clots were skimmed off. The blood was then transfused back to the dog using a standard in‐line blood filter. Approximately 58% of the dog's blood volume was autotransfused in less than 2 hours, thereby meeting the criteria for massive transfusion. Surgery was aborted after hemostasis was achieved by ligation of the vessel and packing of the surgical site. Two units of fresh frozen plasma were administered postoperatively due to the development of a coagulopathy. Hemoglobinuria developed but resolved within 18 hours. Three days later, completion of the surgical procedure was performed without incident. The dog was discharged 4 days after the initial surgery. Marked swelling of the affected limb developed, but resolved after the sixth day. No other significant complications developed. New or Unique Information Provided In this case report, the authors describe the successful management of catastrophic hemorrhage with autotransfusion performed in the absence of sterile collection, cell washing, or anticoagulation. Although not ideal, autotransfusion under these conditions can be lifesaving in situations of massive hemorrhage. This case also highlighted the employment of a damage control surgical strategy.

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Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 99%