Measurement and Correlation of the Solubility of Aminocaproic Acid in Some Pure and Binary Solvents

Abstract

The solubilities of aminocaproic acid in four monosolvents (isopropanol, methyl acetate, ethyl acetate, and water) and three binary solvents (methanol–water, ethanol–water, and dimethylformamide–water) were measured by the static analytical method from 283.15 to 323.15 K at atmospheric pressure. In monosolvents, the solubility increases with the increase of temperature. Also, the solubility of aminocaproic acid in water is much higher than that in other organic solvents. In binary solvents, the solubility increases with the increase of the temperature and the mole fraction of water. The solubility data was well correlated by the Apelblat equation, λh equation, and NRTL equation, and the mixing properties of enthalpy, Gibbs energy, and entropy have also been discussed.

Solid–Liquid Equilibrium Behavior and Thermodynamic Analysis of Dibenzoylmethane in Different Pure and Binary Solvent Systems from 278.15 to 318.15 K

“…As a thermodynamic property, solubility is affected by molecular parameters such as solvent polarity, hydrogen bond donor, hydrogen bond acceptor, and dielectric constant. ,, The molecular structure is conducive to the formation of hydrogen bonds between solute molecules and solvent molecules, thus affecting the solubility. The chemical structure of DBM is shown in Figure , which shows only two hydrogen bond donors in the structure.…”

Determination of Solubility and Thermodynamic Analysis of Solubility Behavior of 2,5-Furandicarboxylic Acid in Water and Ether Binary Solvent System

“…To determine the dissolving property of a solute in a solvent system, the activity number method, state equation method, or empirical equation method is generally employed. − Among them, the state equation method has good accuracy for solid liquid equilibrium of nonpolar systems, but it is still difficult to study strongly polar systems, or complex or multivariate systems. For this reason, activity coefficient models (NRTL model, Wilson model) and semiempirical equations (including Apelblat equation, van’t Hoff equation, λ h equation) , are used to study the dissolving property of FDCA in this paper.…”

Solubility Measurement and Data Correlation of Clopidogrel Hydrogen Sulfate (Form I) in Four Binary Solvents Systems at Temperature from 278.15 to 318.15 K

“…A and B represent the nonideality of the change of activity coefficient in the actual solution, and C reflects the effect of temperature on the fusion enthalpy. 22,23 3.2. λh Equation. Buchowski et al 24 proposed the λh equation according to the study of the solubility of the phenolic compounds, benzoic acid, the activity of solvents, and the vapor pressure of saturated solutions.…”

“…The modified Apelblat equation , assumes that the enthalpy of the solution has a linear function with temperature, and a simplified equation expressing the state of solid–liquid equilibrium is derived from the Clausius–Clapeyron equation, which can be expressed as eq where x 1 is the mole fraction solubility of solute, T is the absolute experiment temperature, and A , B , and C are model parameters of the equation. A and B represent the nonideality of the change of activity coefficient in the actual solution, and C reflects the effect of temperature on the fusion enthalpy. , …”