Memory self-assessment and performance in aged diabetics and non-diabetics

Tun, Patricia A.; Perlmuter, Lawrence C.; Russo, Patrícia A.; Nathan, David M.

doi:10.1080/03610738708259317

Cited by 73 publications

(47 citation statements)

References 14 publications

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“…Quite identical to previously reported data [1][2][3][4], we found diabetes to be associated with increased risk of cognitive impairment comparing healthy individuals. We evaluated the possible role of hyperinsulinemia in inducing dementia by comparing two drugs that differ in their mechanism of lowering blood glucose.…”

Section: Discussionsupporting

confidence: 78%

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Cognitive Impairment in Type 2 Diabetic Patients Treated with Metformin in Comparison with those Taking Glibenclamide

M¹,

Siavash²,

Ki³

et al. 2014

JNSK

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Section: Discussionsupporting

confidence: 78%

“…Poor cognitive function is reported to be associated with Type 2 diabetes, although the etiology of this phenomenon is still unclear [1][2][3]. Comparing with non-diabetic individuals, the incidence of dementia in diabetic patients has increased about 50-100%, in both Alzheimer disease (AD) and vascular dementia [4].…”

Section: Introductionmentioning

confidence: 99%

Cognitive Impairment in Type 2 Diabetic Patients Treated with Metformin in Comparison with those Taking Glibenclamide

M¹,

Siavash²,

Ki³

et al. 2014

JNSK

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“…Of the 42 total studies, 3 (7%) did not provide enough information to be included in the OR or point prevalence calculations. Two of these three studies (32,33) reported only the statistical comparison of the mean depression scale scores of diabetic versus nondiabetic subjects, and the other (34) reported only lifetime rates of depression.…”

Section: Methodsmentioning

confidence: 99%

The Prevalence of Comorbid Depression in Adults With Diabetes

Anderson¹,

Freedland²,

et al. 2001

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OBJECTIVE -To estimate the odds and prevalence of clinically relevant depression in adults with type 1 or type 2 diabetes. Depression is associated with hyperglycemia and an increased risk for diabetic complications; relief of depression is associated with improved glycemic control. A more accurate estimate of depression prevalence than what is currently available is needed to gauge the potential impact of depression management in diabetes. RESEARCH DESIGN AND METHODS -MEDLINE and PsycINFO databases andpublished references were used to identify studies that reported the prevalence of depression in diabetes. Prevalence was calculated as an aggregate mean weighted by the combined number of subjects in the included studies. We used 2 statistics and odds ratios (ORs) to assess the rate and likelihood of depression as a function of type of diabetes, sex, subject source, depression assessment method, and study design.RESULTS -A total of 42 eligible studies were identified; 20 (48%) included a nondiabetic comparison group. In the controlled studies, the odds of depression in the diabetic group were twice that of the nondiabetic comparison group (OR ϭ 2.0, 95% CI 1.8 -2.2) and did not differ by sex, type of diabetes, subject source, or assessment method. The prevalence of comorbid depression was significantly higher in diabetic women (28%) than in diabetic men (18%), in uncontrolled (30%) than in controlled studies (21%), in clinical (32%) than in community (20%) samples, and when assessed by self-report questionnaires (31%) than by standardized diagnostic interviews (11%).CONCLUSIONS -The presence of diabetes doubles the odds of comorbid depression. Prevalence estimates are affected by several clinical and methodological variables that do not affect the stability of the ORs.

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“…Clinical and subclinical expressions of depression are present in Ͼ25% of patients with type 1 or type 2 diabetes (6)(7)(8)(9)(10)(11)(12)(13)(14) and have adverse effects on functioning and quality of life (15,16). The existing literature is not consistent and clear with regard to the association between depression and poor glycemic control.…”

mentioning

confidence: 99%

Depression and poor glycemic control: a meta-analytic review of the literature.

et al. 2000

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Hyperglycemia has been linked to the development of diabetic complications (1). Treatments that lower blood glucose levels reduce the risks of retinopathy, neuropathy, and nephropathy in patients with type 1 (2,3) or type 2 (4,5) diabetes. Accordingly, maintenance of good glycemic control is the focus of diabetes therapy, and the importance of other clinical factors is judged largely in relation to their effects on this parameter.Clinical and subclinical expressions of depression are present in Ͼ25% of patients with type 1 or type 2 diabetes (6-14) and have adverse effects on functioning and quality of life (15,16). The existing literature is not consistent and clear with regard to the association between depression and poor glycemic control. Such an association would suggest the possibility that depression treatment might have favorable effects on diabetic outcomes. We surveyed the scientific literature, identified studies that measured the association of depression (either by symptoms or the diagnosis) with glycemic control, and performed a metaanalysis to assess the reliability and strength of any association. RESEARCH DESIGN ANDMETHODS -Medline and PsycINFO were used to locate studies published in the last 25 years that reported the association of depression with glycemic control in adult diabetic subjects. The reference lists of these articles were examined to identify additional studies, and this led to the consideration of several unpublished papers and manuscripts. Inclusion and exclusion criteriaStudies were limited to adult participants (Ն18 years of age), to those that assessed glycemic control using a measure of glycohemoglobin (denoted as GHb within this article) (17,18), and to those that measured depression and GHb coincident to the study evaluation. Studies with Ͻ25 patients, those neither published nor available in English, and those that ascertained only a history of depression were excluded. Subjects in the included studies were patients diagnosed with type 1 or type 2 diabetes; studies of subjects with impaired glucose tolerance, borderline diabetes, or gestational diabetes were not considered. Studies were included without regard to the way the depression-glycemic control association was tested. In some studies, depression was the independent variable and glycemic control the dependent variable. Other studies used the reverse approach, and some reported only the correlation between the 2 variables.Study procedures and statistical analysis Study characteristics were recorded, and the studies were categorized by methodology. Type of diabetes and method of depression assessment were recorded, and effect sizes (ESs) were examined in relation to these factors. The diagnosis of depression (major depressive disorder) was established by using structured or semistructured clinical interviews and the diagnostic criteria in use at the time of the study (e.g., American Psychiatric Association' s Diagnostic and Statistical Manual of Mental Disorders [19,20] Depression and Poor Glycemic ControlA meta-an...

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Memory self-assessment and performance in aged diabetics and non-diabetics

Cited by 73 publications

References 14 publications

Cognitive Impairment in Type 2 Diabetic Patients Treated with Metformin in Comparison with those Taking Glibenclamide

Cognitive Impairment in Type 2 Diabetic Patients Treated with Metformin in Comparison with those Taking Glibenclamide

The Prevalence of Comorbid Depression in Adults With Diabetes

Depression and poor glycemic control: a meta-analytic review of the literature.

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