Metabolic Syndrome Prevalence among Prediabetic and Normoglucotolerant Women

Abstract

Prediabetes is a known risk factor for type 2 diabetes and lead to long term complications such as cardiovascular diseases. In Cameroon, they are limited data dealing with prediabetes prevalence among Cameroonians. Our study objective was to estimate the prevalence of metabolic syndrome among prediabetic women and normoglyceamic women. Methods:A total of 200 women (100 prediabetic women and 100 normoglyceamic) participated in the study, they were aged between 20-55 years. For their studied data, they were referred to the Andre Fouda Medical Fundation in Yaounde. Metabolic syndrome was diagnosed using Adult Treatment Panel-III [ATP-III] 2001 guidelines and prediabetes was defined as impaired fasting plasma glucose ranged between 6.1-6.9 mmol/l. Results:The frequency of various cardiovascular risk factors was not different among the two group of study; only fasting blood glucose was significantly high among prediabetics compared to normoglyceamics women. The mean age in prediabetic women was 34.34 ± 8.96 years and 35.48 ± 9.88 years among normoglyceamic women. Among the prediabetic population, a total 61% of patients had hyperglyceamia, 59% had hypertension, 58% had increased waist circumference and 56% were diagnosed with metabolic syndrome. The most common abnormalities in normoglyceamic women was hypertension (58%), increased waist circumference (53%) and low HDL (52%). Metabolic syndrome was diagnosed in 23% of normoglyceamic women. Prediabetics women had a relative high risk of metabolic syndrome 2.43 compared to normoglyceamics women. Conclusion:This study shows that prediabetes is associated with increased prevalence of metabolic syndrome among Cameroonian women. Lifestyle interventions and medication should be instituted to avoid complications among prediabetes.

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