Metabolism of S35-Parathion in the House Fly1

Nakatsugawa, Tsutomu; Tolman, N.M.; Dahm, Paul A.

doi:10.1093/jee/62.2.408

Cited by 24 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No resistance was detected in Þeld populations of B. brassicae in United Kingdom to demeton-S-methyl (Furk and Roberts 1985), another phosphorothioate insecticide like chlorpyrifos and profenofos. Phosphorothioates are considered less likely to be attacked hydrolytically (Metcalf 1967, Nakatsugawa et al 1969, Oppenoorth 1971. Endosulfan may also be less vulnerable to metabolic attack because of its carbon-chloride bonds, which rarely occur in biological systems.…”

Section: Discussionmentioning

confidence: 99%

Development of Insecticide Resistance in Field Populations of <I>Brevicoryne brassicae</I> (Hemiptera: Aphididae) in Pakistan

Ahmad¹,

Akhtar²

2013

jnl. econ. entom.

View full text Add to dashboard Cite

Cabbage aphid Brevicoryne brassicae (L.) (Hemiptera: Aphididae) is a serious pest of crucifers in Pakistan. After incidences of poor control by recommended insecticides, the current study was undertaken to find out the status of insecticide resistance in Pakistani B. brassicae. Apterous adult aphids were bioassayed from 2006 to 2010 for their response to 12 insecticides using an adult immersion method. No or very low levels of resistance was found to endosulfan; and the organophosphates: chlorpyrifos and profenofos. Resistance to methomyl; emamectin benzoate; the pyrethroids: cypermethrin, lambdacyhalothrin, bifenthrin and deltamethrin; and the neonicotinoids: imidacloprid, acetamiprid, and thiamethoxam; increased progressively in concurrence with their regular use on vegetables. B. brassicae resistance to these insecticides remained very low to low in 2007 and 2008, but then it increased to moderate to high levels in 2009 (except cypermethrin and bifenthrin) and 2010. Under heavy infestations of this aphid, the application of insecticides having no, very low and low resistance is recommended in rotation.

show abstract

Section: Discussionmentioning

confidence: 99%

Development of Insecticide Resistance in Field Populations of <I>Brevicoryne brassicae</I> (Hemiptera: Aphididae) in Pakistan

Ahmad¹,

Akhtar²

2013

jnl. econ. entom.

View full text Add to dashboard Cite

show abstract

“…Nakatsugawa et al (48,49) reported that DETP was released from PTN in eucaryotes primarily by microsomal oxygenases but not by non-oxidative hydrolytic enzymes. The hydrolysis of PTN by "thionase" enzymes was reported by Matsumura and Hogendijk (42) to occur in PTN-resistant houseflies, but this postulated non-oxidative hydrolysis has since been questioned (48,71). One of the only reports of desulfuration of a thioate to an oxon by a microorganism concerned the intra-cellular desulfuration of Dyfonate to dyfoxon by soil fungi (16).…”

Section: Discussionmentioning

confidence: 99%

Parathion utilization by bacterial symbionts in a chemostat

Daughton¹,

Hsieh²

1977

Appl Environ Microbiol

View full text Add to dashboard Cite

A continuous-culture device was used to select and enrich for microorganisms, from sewage and agricultural runoff, that were capable of using the organophosphorus insecticide parathion as a sole growth substrate. Parathion was dissimilated by the highly acclimated symbiotic activities of Pseudomonas stutzeri, which non-oxidatively and cometabolically hydrolyzed the parathion to ionic diethyl thiophosphate and p-nitrophenol, and P. aeruginosa, which utilized the p-nitrophenol as a sole carbon and energy source. Ionic diethyl thiophosphate was found to be inert to any transformations. Methyl parathion was dissimilated in an analogous way. The device functioned as a chemostat with parathion as the growth-limiting nutrient, and extraordinarily high dissimilation rates were attained for parathion (8 g/liter per day) and for p-nitrophenol (7 g/liter per day). This is the first report of parathion utilization by a defined microbial culture and by symbiotic microbial attack and of dissimilation of an organophosphorus pesticide in a chemostat. Continuous-cultivation techniques have rarely been used for studying the interactions of microorganisms and xenobiotics, e.g., microbial degradation of pesticides and toxic wastes.

show abstract

“…Since a partially purified enzyme preparation was used, it seems improbable that the mixed-function oxidases were involved in the reaction. However, according to Welling et al (1971) and Nakatsugawa et al (1969), they could not reproduce the results with [14C]parathion or [35S]parathion. Thus most of the recent reviewers Oppenoorth, 1971; Wilkinson, 1971) concluded that phosphates are preferred substrates for hydrolysis by phosphatase, but phosphorothioates probably are not.…”

Section: Malathionmentioning

confidence: 98%