Metabolites of Dactylaria lutea: The structures of dactylariol and the antiprotozoal antibiotic dactylarin.

Becker, Anna Maria; Rickards, Rodney W.; Schmalzl, K. J.; Yick, H. C.

doi:10.7164/antibiotics.31.324

Cited by 47 publications

(52 citation statements)

References 13 publications

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“…In addition to the above metabolites C. queenslandicum IFM 51121 co-produced new antibacterial compounds related to members of the dihydronaphthaquinone group5-7) which were given the name chrysoqueen (1) and chrysolandol (2).…”

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confidence: 99%

Isolation and Structure Elucidation of Two New Antibacterial Compounds Produced by Chrysosporium queenslandicum.

et al. 2002

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During our investigation on bioactive antifungal pigments the strain Chrysosporium queenslandicum IFM 51121 was found to produce a series of darkish to reddish pigments which were identified as naphthaquinone-type altersolanols A, B, C1-3). Moreover, a new antifungal compound (queenslandon)4) was isolated as a new representative of the zearalenone family of mycotoxin. In addition to the above metabolites C. queenslandicum IFM 51121 co-produced new antibacterial compounds related to members of the dihydronaphthaquinone group5-7) which were given the name chrysoqueen (1) and chrysolandol (2).In this paper we report fermentation, isolation, physicochemical properties and the structure elucidation of 1 and 2. the residue was dissolved in a small amount of ethyl acetate and further purification and separation was achieved by preparative thin-layer chromatography on silica gel plates (Merck silica gel 60 F254) using mixtures of v/v) and (80:20; v/v). The compounds were disclosed on the TLC plates due to their yellowish fluorescence in UV254 light.

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confidence: 99%

Isolation and Structure Elucidation of Two New Antibacterial Compounds Produced by Chrysosporium queenslandicum.

et al. 2002

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“…Related tetrahydroanthraquinone derivatives were produced by fungi such as Alternaria eichhorniae [10], Alternaria porri [15], Alternaria solani [12, 16ϳ19], Auxarthron umbrinum [20], Chrysosporium queenslandicum [21], Dactylaria lutea [22,23], Dermocybe sp. [24], Phomopsis juniperovora [25], Pleospora sp.…”

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confidence: 99%

Tetrahydrobostrycin and 1-Deoxytetrahydrobostrycin, Two New Hexahydroanthrone Derivatives, from a Marine-derived Fungus Aspergillus sp.

Nakazawa

Ukai

et al. 2008

J Antibiot

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Two new hexahydroanthrones, tetrahydrobostrycin (1) and 1-deoxytetrahydrobostrycin (2), were isolated from a marine-derived fungus Aspergillus sp. strain 05F16 collected at the coral reef of Manado, Indonesia, together with bostrycin and abscisic acid. The structures of new compounds were determined on the basis of their spectral data. Compound 1 showed weak antibacterial activity against Staphylococcus aureus and Escherichia coli and 2 against S. aureus.

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“…Dactylarin and dactylariol have been isolated from D. lu tea [12,13] and the dactylfungins were obtained from D. parvispora [14]. In both cases, the produc ing strains were isolated from soil and have not been shown to be nematode-trapping.…”

Section: Resultsmentioning

confidence: 99%

New Biologically Active Compounds from the Nematode-Trappmg Fungus Arthrobotrys oligospora Fresen

Stadler¹,

Sterner²,

Anke³

1993

Zeitschrift Für Naturforschung C

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Dedicated to Professor D r. W olfgang Steglich on the occasion o f his 60 th birthdayArthrobotrys oligospora, Nematode-Trapping Fungi, Oligosporon, Oligosporols A and B, Cytotoxic ActivitiesThe isolation, structural elucidation and biological activities of oligosporon (1), oligosporol A (2) and oligosporol B (3), three new antibiotics from cultures of the predacious deuteromycete, Arthrobotrys oligospora, are reported. The structures were elucidated by means of high resolution mass and high field N M R spectroscopy. The compounds exhibited weak antimicro bial, cytotoxic and hemolytic effects, but were not active towards the nematode Caenorhabditis elegans. Other Arthrobotrys species were also found to produce these or similar compounds.

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Metabolites of Dactylaria lutea: The structures of dactylariol and the antiprotozoal antibiotic dactylarin.

Cited by 47 publications

References 13 publications

Isolation and Structure Elucidation of Two New Antibacterial Compounds Produced by Chrysosporium queenslandicum.

Isolation and Structure Elucidation of Two New Antibacterial Compounds Produced by Chrysosporium queenslandicum.

Tetrahydrobostrycin and 1-Deoxytetrahydrobostrycin, Two New Hexahydroanthrone Derivatives, from a Marine-derived Fungus Aspergillus sp.

New Biologically Active Compounds from the Nematode-Trappmg Fungus Arthrobotrys oligospora Fresen

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