Methodical approaches to health risk assessмеnt of heterogeneous environmental factors based on evolutionary models

Zaitseva, N.V.; Трусов, П. В.; Shur, P.Z.; Kiryanov, D.A.; Chigvintsev, Vladimir M.; Tsinker, M.Yu.

doi:10.21668/health.risk/2013.1.02

Cited by 7 publications

(5 citation statements)

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“…Dust is emitted during all, except for hydro-chemical, metallurgical processes, especially in rooms where the finely dispersed source material is produced, poured, loaded, transported, and unloaded. Dust settles on the floor, walls, and equipment (Roslaya et al, 2001; Zaytseva et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

The effect of work environment on the biochemical profile of workers operating at the Ust-Kamenogorsk Titanium and Magnesium Plant

et al. 2020

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This study explored biochemical parameters of blood in workers operating in the main workshops at the Ust-Kamenogorsk Titanium and Magnesium Plant: magnesium (Mg) workshop (furnace operator, chlorinator operator, and electrolyzer operator), titanium tetrachloride workshop (mill operator and titanium (Ti) production operator), and Ti sponge workshop (reduction furnace operator, knockout operator, and crushing machine operator). The control group consisted of 112 male workers, whose duties were not related to similar occupational hazards (plumbers, electricians, janitors cleaning the administrative building, security guards, and carpenters). The activity of gamma-glutamyl transferase, aspartate aminotransferase, alanine aminotransferase, creatine phosphokinase, lactate dehydrogenase, cholinesterase, alkaline phosphate, and α-amylase and the concentration of serum calcium, Mg, phosphorus, and chloride ion were measured. To clarify the nature of pathological changes that occur in the body of mammals under the influence of toxic gases and dust, this study also included 130 sexually mature, white female rats. Animals and workers were exposed to examination of the same indicators. Changes in test results of enzymes and minerals indicated a negative impact that harmful production factors may have had on the bodies of workers. Findings showed significant fluctuations in enzyme and mineral blood profiles of workers as compared to controls. In the test animals, changes in the enzyme activity and mineral blood composition were as diverse as in the workers. These findings will be useful when identifying markers of a negative impact of harmful substances in an industrial workplace and when developing measures to prevent employees from developing an occupational disease.

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Section: Introductionmentioning

confidence: 99%

The effect of work environment on the biochemical profile of workers operating at the Ust-Kamenogorsk Titanium and Magnesium Plant

et al. 2020

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“…The group of researchers, including the authors of this article, is working on a multilevel mathematical model of damage accumulation in a human body associated with environmental exposure (chemical, physical, social, etc., factors) [ 7 , 8 ]. At the “macro-level”, we are analyzing the interaction between organs and systems with the help of ordinary differential systems that describe the evolution of damage.…”

Section: Introductionmentioning

confidence: 99%

A Multiphase Flow in the Antroduodenal Portion of the Gastrointestinal Tract: A Mathematical Model

Трусов

Zaitseva

Kamaltdinov

2016

Computational and Mathematical Methods in Medicine

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A group of authors has developed a multilevel mathematical model that focuses on functional disorders in a human body associated with various chemical, physical, social, and other factors. At this point, the researchers have come up with structure, basic definitions and concepts of a mathematical model at the “macrolevel” that allow describing processes in a human body as a whole. Currently we are working at the “mesolevel” of organs and systems. Due to complexity of the tasks, this paper deals with only one meso-fragment of a digestive system model. It describes some aspects related to modeling multiphase flow in the antroduodenal portion of the gastrointestinal tract. Biochemical reactions, dissolution of food particles, and motor, secretory, and absorbing functions of the tract are taken into consideration. The paper outlines some results concerning influence of secretory function disorders on food dissolution rate and tract contents acidity. The effect which food density has on inflow of food masses from a stomach to a bowel is analyzed. We assume that the future development of the model will include digestive enzymes and related reactions of lipolysis, proteolysis, and carbohydrates breakdown.

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“…There have appeared works developing and completing the traditional approaches to assessment of chemical risks and allowing for assessment of the health risks at exposure to chemical, as well as to a number of physical factors: noise, electromagnetic radiation, lifestyle factors, etc., using a single methodological approach thereto. [14].…”

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confidence: 99%

Social and hygienic monitoring today: state and prospects in conjunction with the risk-based supervision

Зайцева¹,

May²,

Kiryanov³

et al. 2016

Health Risk Analysis

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It is shown in the article that since the establishment in 1992 and until now the social and health monitoring (SHM) operates as a complex open system of extended collection and processing of heterogeneous data about the parameters of the environment, socio-economic indicators of living of the population of the country's regions, medical and demographic characteristics of society as a whole and of individual population groups. As part of the SHM system Rospotrebnadzor annually performs hundreds of thousands of instrumental measurements of objects in the environment of the Russian Federation. These federal and regional information assets have tremendous analytical capacity and allow a knowledge-based processing of information in the "health-environment" system for a variety of management tasks of sanitary and epidemiological situation.Changing

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Methodical approaches to health risk assessмеnt of heterogeneous environmental factors based on evolutionary models

Cited by 7 publications

References 0 publications

The effect of work environment on the biochemical profile of workers operating at the Ust-Kamenogorsk Titanium and Magnesium Plant

The effect of work environment on the biochemical profile of workers operating at the Ust-Kamenogorsk Titanium and Magnesium Plant

A Multiphase Flow in the Antroduodenal Portion of the Gastrointestinal Tract: A Mathematical Model

Social and hygienic monitoring today: state and prospects in conjunction with the risk-based supervision

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