Methyl Bromide Poisoning : A Proposal for a New Clinical Classification and the Results of Its Application to Fifty-Seven Cases So Far Reported in Japan

Araki, Shunichi; Ushio, Köichi; Abe, Akira; Uehara, Koichiro; Suwa, K

doi:10.1539/joh1959.13.419

Cited by 8 publications

(3 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The occurrence of EEG abnormalities confirms observations in acute intoxication (Araki et al, 1971;Merellio et al, 1974 and others), but it was not reported earlier in apparently healthy workers. The abnormalities possibly reflect an early stage in the development of encephalopathy.…”

Section: Discussionsupporting

confidence: 88%

“…Application may be hazardous to the health of the workers, especially inside greenhouses. Severe and sometimes fatal intoxication has been reported in the United States (Hine, 1969), Japan (Araki et al, 1971), France (Merellio et al, 1974), Spain (Garcia Rico et al, 1974) and the Netherlands (Hartzuiker, 1968). A few years ago, the Dutch Labour Inspectorate made a study of the use of the bromine level in blood as an indicator of the early effects of methyl bromide exposure.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Bromine in blood, EEG and transaminases in methyl bromide workers.

Verberk¹,

Rooyakkers-beemster²,

Vlieger³

et al. 1979

Occupational and Environmental Medicine

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 88%

mentioning

confidence: 99%

Bromine in blood, EEG and transaminases in methyl bromide workers.

Verberk¹,

Rooyakkers-beemster²,

Vlieger³

et al. 1979

Occupational and Environmental Medicine

View full text Add to dashboard Cite

show abstract

“…Myoclonus after methyl bromide poisoning has been observed in the past mainly as a consequence of accidental leakage (1) or voluntary intoxication (2) from fire extinguishers. The major use of methyl bromide is presently as insect fumigant (3,4).…”

mentioning

confidence: 99%

Methyl bromide myoclonus: an electrophysiological study

Uncini

Basciani

Muzio

et al. 2009

Acta Neurologica Scandinavica

View full text Add to dashboard Cite

We report a case of myoclonus from overnight exposure to methyl bromide. Myoclonus was either spontaneous or induced by somatosensory stimulation or voluntary movements, multifocal and sometimes generalized. Median SEP showed normal size P14‐N20, but giant parietal P25, N33 and frontal P22‐N30 waves. Back‐averaging showed a biphasic EEG spike of maximal amplitude at the central region contralateral to the corresponding myoclonic jerk recorded from abductor pollicis brevis and preceding it by a short interval consistent with conduction in corticospinal pathways. Long latency reflexes from cutaneous and mixed nerve stimulation were enhanced. The above electrophysiological findings suggest that myoclonus following methyl bromide poisoning belongs to the cortical reflex myoclonus category.

show abstract