Methyl (p-hydroxybenzoyl) acetate and an alkaloid, bellendine, from Bellendena montana

Natural Products Isolated from Endemic Tasmanian Vascular Plants

“…This species contains a large number of structurally diverse indole alkaloids. This includes aristoserratine (34), [14] the structure of which was secured by X-ray crystallography, [15] peduncularistine (35), triabunnine (36), aristolarine (37), [16] tasmanine (38), aristoteline (39), [17] hobartine (40), and sorelline (41) ( Fig. 5).…”

“…10). [40] The structure of bellendine was secured by X-ray crystallography. [41] A separate phytochemical investigation indicated that bellendine (62) was the major alkaloid in B. montana flowers, and its isomer isobellendine (63) represented the major alkaloid of the 'other parts of the plant' examined.…”

Biogenesis of Proteaceous Alkaloids

“…Since the discovery {1] in 1971 of bellendine (G 2), the first base recorded [1][2][3][4][5] and two endemic in New Caledonia (Knightia deplanchei VIEILL. ex BRONGN. GRIS, Knightia strobilina LABILL.)…”

Dilobenol A–G, Diprenylated Dihydroflavonols from the Leaves of Dilobeia thouarsii

“…[1] Its wood is resistant to pathogens such as fungi or insects and is used in house construction and carpentry. They exhibited moderate growth inhibitory activities against Staphylococcus aureus, Vibrio spp., Bacillus spp, and Plasmodium falciparum without significant toxicity against mammalian cell line L- 6. Early phytochemical investigations of other Proteaceae showed them to be rich in the biosynthesis of tropane alkaloids, [4] naphtoquinones, [5] phenols and macrocyclic phenols, [6][7][8] aryl and cyanogenic glycosides. It is also used to prevent the risks of abortion.…”

“…[3] for their antibacterial, antiplasmodial and cytotoxic activities. They exhibited moderate growth inhibitory activities against Staphylococcus aureus, Vibrio spp., Bacillus spp, and Plasmodium falciparum without significant toxicity against mammalian cell line L- 6. Early phytochemical investigations of other Proteaceae showed them to be rich in the biosynthesis of tropane alkaloids, [4] naphtoquinones, [5] phenols and macrocyclic phenols, [6][7][8] aryl and cyanogenic glycosides. [9][10][11][12] These compounds displayed a wide spectrum of biological activities, for example, antimicrobial, [13][14] antioxidant, [15] cytotoxic, [8] anti-HIV, [16] anti-inflammatory [17] and antiplasmodial.…”