Mg2+-doped carbon dots synthesized based on Lycium ruthenicum in cell imaging and promoting osteogenic differentiation in vitro

Rutin-Loaded Carbon Dots for Management of Methicillin-Resistant Staphylococcus aureus Lung Infection

“…This was most likely due to particle aggregation in the PBS suspension fluid that differed from the TEM preparation solution. High-resolution TEM indicated the CDs possessed distinct lattice strips and a lattice spacing of 0.2 nm (Figure S1B) corresponding to the (100) plane of graphite as previously reported . However, the R-CDs lattice strips differed and were distinct from the CDs strips, indicating successful surface modification of CDs by the self-assembly method was successful.…”

“…High-resolution TEM indicated the CDs possessed distinct lattice strips and a lattice spacing of 0.2 nm (Figure S1B) corresponding to the (100) plane of graphite as previously reported. 23 However, the R-CDs lattice strips differed and were distinct from the CDs strips, indicating successful surface modification of CDs by the self-assembly method was successful. The zeta potentials of the CDs surfaces also differed and the CDs surfaces were positively charged while those of the R-CDs were negatively charged (Figure 1C).…”

Functional carbon dots derived from biomass and plastic wastes

“…CDs typically have a spherical shape with particle sizes <10 nm and primarily are comprised of amorphous carbon and nanocrystalline regions of sp 2 hybridized graphitic carbon. These nanomaterials exhibit several desirable properties, including stable photoluminescence, [3][4][5][6] low toxicity, 7 good biocompatibility 8,9 and environmental compatibility, 10 ease of surface modification 11 and stable chemical properties, 12 making them useful for various applications such as fluorescent labeling, [13][14][15][16] bio-bacterial chemicals, 17 photocatalysis, [18][19][20] and flame retardation. 21 The preparation methods of CDs can be divided into top-down and bottom-up approaches, with the primary difference being the sources of CDs.…”

Recent advances in composite hydrogels: synthesis, classification, and application in the treatment of bone defects

“…134 Carbon dots have been shown to upregulate the expression of osteogenesis-related genes ( ALP , RUNX2 , OCN , BSP ) and enhance stromal differentiation via the reactive oxygen species (ROS)-mediated MAPK pathway, which in turn enhances osteogenic differentiation. 135 In addition, endoplasmic reticulum (ER) stress is critical for promoting osteogenic differentiation. When CDs stimulate cells to undergo ER stress, the excretion of unfolded or misfolded proteins from the ER can be accelerated to restore their stability, thereby accelerating the efficiency of osteogenic protein synthesis and processing to some extent.…”