“…The stable and reproducible behaviour of micellar mobile phases allows the accurate prediction of the retention of solutes with a model that can also be used to optimise the separation of mixtures of solutes [23]. MLC has proved to be a useful technique in the determination of diverse groups of compounds [25][26][27][28][29].…”
“…The stable and reproducible behaviour of micellar mobile phases allows the accurate prediction of the retention of solutes with a model that can also be used to optimise the separation of mixtures of solutes [23]. MLC has proved to be a useful technique in the determination of diverse groups of compounds [25][26][27][28][29].…”
“…The simultaneous elution of hydrophobic and hydrophilic analytes is possible [27,28] without needing a gradient elution, and direct injection of physiological samples becomes feasible due to the solubility of proteins in the micelles. MLC has proved to be a useful technique in the determination of diverse groups of compounds [29][30][31][32][33].…”
“…FTIR spectra were recorded on MIDAC M 2000 spectrometer. 1H-NMR spectra were recorded in CDCl 3 on Bruker (400 MHz). Mass spectra (EI-MS) were measured on Finnigan MAT-312 instruments.…”
Section: Experimental Generalmentioning
confidence: 99%
“…Sulfonamides exhibit numerous pharmacological activities [1][2][3] and sulfonamide antibiotics are among the most common instigators of allergic or hypersensitivity reactions [4][5][6]. α-Glucosidase (α-D-glucosideglucohydrolase, EC 3.2.1.20)hydrolyzes the 1,4-glycosidic linkage from the non-reducing end of the α-glucosides [7][8][9].Its inhibitors retard the liberation of Dglucose resulting in delay glucose absorption [10].…”
Purpose: To synthesize a series of new N-(2,3-dimethylphenyl) 27.20 ± 0.24 to 5.20 ± 0.41 %,. Conclusion: Compound 5f is the most potent antibacterial while 5j is the best α-glucosidase inhibitor; 5e showed the least cytotoxicity.
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