Microbial contamination of enteral feeding solution and its prevention

Oie, Shigeharu; Kamiya, Akira; Hironaga, Kyozo; Koshiro, Akira

doi:10.1016/0196-6553(93)90205-i

Cited by 23 publications

(22 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1,2 Environmental sources associated with cross-infection have included contaminated disinfectants, sinks, adhesive tape, scalp vein needles, intravenous solutions, saline bottles and soap. [3][4][5][6][7][8] Often, however, no point source is identified and spread via contaminated hands of healthcare workers is thought to be an important mode of transmission in hospital. 8 S. marcescens does not normally constitute part of the intestinal flora of neonates, but the gastrointestinal tract may become an important reservoir in outbreaks.…”

Section: Introductionmentioning

confidence: 99%

What is the best screening method to detect Serratia marcescens colonization during an outbreak in a neonatal intensive care nursery?

Giles

Harwood

Gosling

et al. 2006

Journal of Hospital Infection

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

What is the best screening method to detect Serratia marcescens colonization during an outbreak in a neonatal intensive care nursery?

Giles

Harwood

Gosling

et al. 2006

Journal of Hospital Infection

View full text Add to dashboard Cite

“…marcescens and B. cepacia readily contaminate medical preparations, they are opportunistic bacteria that have been linked to the outbreak of infections in hospitals, and these infections must be taken seriously. [5][6][7][8][9][10][11] P. aeruginosa, S. aureus, and C. albicans are typical pathogenic organisms and often contaminate medical preparations when prepared or manipulated in hospital. 5,9,10) We evaluated the viability of these bacteria in preparations packaged for single use only.…”

Section: Discussionmentioning

confidence: 99%

“…[5][6][7][8][9][10][11] P. aeruginosa, S. aureus, and C. albicans are typical pathogenic organisms and often contaminate medical preparations when prepared or manipulated in hospital. 5,9,10) We evaluated the viability of these bacteria in preparations packaged for single use only. These bacterial species proliferated rapidly at 30°C in albumin preparations, preparations containing albumin (such as urokinase and interferon), fat emulsions, and a preparation containing fat emulsion (propofol) (Figs.…”

Section: Discussionmentioning

confidence: 99%

Microbial Viability in Preparations Packaged for Single Use

Obayashi

Oie

Kamiya

2003

Biological & Pharmaceutical Bulletin

View full text Add to dashboard Cite

We evaluated microbial viability in preparations packaged for single use only which mandate that residual solution be discarded such as albumin and globulin preparations as blood products, preparations containing albumin (such as urokinase and interferon), fat emulsions, and a preparation containing fat emulsions (propofol). In most preparations, Serratia marcescens and Burkholderia cepacia proliferated rapidly at 30 degrees C. However, in globulin preparations containing 1-2.25% glycine to prevent protein degradation (Gamma-Venin P, Venilon-I, Globulin Injection, and Ahlbulin), no growth of S. marcescens and B. cepacia was detected over 24 h at 30 degrees C. For globulin preparations containing 1-2.25% glycine, the injunction to "Discard residual solution after the package has been used" in the package inserts can be revised to "It is possible to use residual solution within 24 h after the package has been used with storage in a cool place."

show abstract

“…Incidence of colonization increases with a more alkaline gastric pH value or with a reduced amount of gastric acid. 33,34 Prerequisites for the development of aspiration pneumonia include the presence of refluxed gastric contents in the distal lung, resident gastric or oropharyngeal pathogens, and loss of immune defenses. Older adults with significant neurologic impairments, who receive enteral feedings, easily possess all three prerequisites.…”

Section: Aspiration Pneumonitismentioning

confidence: 99%

Pulmonary aspiration of enteral feedings: A model for prevention

Ouellette

1995

Journal of Home Health Care Practice

View full text Add to dashboard Cite

As a cost-saving measure, more adults now receive complex home health care services each year. One such service is the safe administration of enteral feedings through a gastrostomy tube for adults with significant neurologic impairments. These adults are at high risk for pulmonary aspiration caused by gastroesophageal reflux of formula and gastric acids. Analysis of the etiology and pathophysiology of pulmonary aspiration, pneumonitis, and pneumonia helps to establish a care plan for prevention.

show abstract

Microbial contamination of enteral feeding solution and its prevention

Cited by 23 publications

References 16 publications

What is the best screening method to detect Serratia marcescens colonization during an outbreak in a neonatal intensive care nursery?

What is the best screening method to detect Serratia marcescens colonization during an outbreak in a neonatal intensive care nursery?

Microbial Viability in Preparations Packaged for Single Use

Pulmonary aspiration of enteral feedings: A model for prevention

Contact Info

Product

Resources

About