Microcystic Adnexal Carcinoma

Clinical Course, Risk Factors, and Treatment of Microcystic Adnexal Carcinoma: A Short Series Report

“…Radiation and chemotherapy have been used as primary and as adjuvant therapy, but the data supporting these forms of treatment are generally lacking. Treatment with MMS has been reported to have a low recurrence rate 8,11,23,24 . Our series supports this finding in that our MMS group remains recurrence free in four cases, whereas a 16.7% (one of six cases) recurrence rate was found after wide excision.…”

Metastatic Microcystic Adnexal Carcinoma: An Autopsy Case

“…Birkby et al 11 reported the first case, a direct invasion and replacement of the bone marrow of the mandible along the mental nerve. Burns et al 12 found not only perineural but also intraneural invasion. In our case, the tumor cells histologically invaded the optic nerve, infiltrated to the subarachnoid space along the optic nerve, and invaded the anterior falax cerebri.…”

“…MICROCYSTIC ADNEXAL carcinoma was first classified as a type of sweat gland carcinoma by Goldstein et al in 1982 1 . This malignant tumor is clinically an aggressive, locally destructive cutaneous neoplasm with a high rate of recurrence, but regional or distant metastasis is rare 2–16 . To date, there have been only two reports of regional metastasis 9,13 and one report of distant metastasis 15 …”

Microcystic Adnexal Carcinoma in the Nasolabial Area: Resection and Reconstruction with a Free Fasciocutaneous Lateral Arm Flap with a Sandwich Technique

“…In this study the recurrence was 30% after simple excision 3 . It is mentioned that Mohs micrographic surgery may more accurately ensure margin status relative to single excision to avoid incomplete excision as another factor of recurrence 12–14 . Regardless of the surgical modalities chosen, a long period of follow‐up is required because of the very aggressive and locally invasive nature of the tumor.…”