Microfibrillar Networks: Polymer Thermoreversible Gels vs Organogels

Abstract

Summary: This paper is intended to review some aspects of fibrillar networks by comparing polymer thermoreversible gels and organogels, the latter being obtained through the self-assembling of small organic molecules. The morphology, the rheological properties and the gelation mechanisms are particularly examined. The possibility of preparing hybrid materials is discussed.

Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement

“…21.2 ). It is essential to determine the gelation temperature of the LOs containing drugs as it serves as a guide for recommending storage conditions for drug-loaded medicated LOs (Díaz et al 2008 ;Dasgupta et al 2009 ;Guenet 2006 The gelation temperature varies depending on the solvent system used when preparing LOs.…”

Lecithin Organogels in Enhancing Skin Delivery of Drugs

“…The gelation temperature can be determined visibly. It is essential to determine the gelation temperature of the LOs containing drugs as it serves as a guide for recommending storage conditions for drug-loaded medicated LOs (Díaz et al 2008 ;Dasgupta et al 2009 ;Guenet 2006 ).…”

Development of span 80-tween 80 based fluid-filled organogels as a matrix for drug delivery

“…In general, physical gels show gel-to-sol phase transition (Tg). [ 1 – 3 ] This property is not shown by the gels formed due to chemical reactions. Tg has been determined by various methods including “dropping ball” technique,[ 4 ] bubble motion[ 5 ] or by the inverted test tube method.…”