Microscale Drug Delivery Systems: Current Perspectives and Novel Approaches

Neguț, Irina; Grumezescu, Valentina; Dorcioman, G.; Socol, G.

doi:10.1016/b978-0-323-52727-9.00001-7

Cited by 4 publications

(4 citation statements)

References 146 publications

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“…Thus, critical factors that influence the design are the selection of the polymerisation conditions and reactor 56 . Preparation of multiple polymers is generally performed using polymerisation methods such as suspension, emulsion, bulk and interfacial polymerisation 55 54 indicating that the polymerisation process can only be classified under two systems, depending on the medium and the phases that exist.…”

Section: Methods Of Encapsulationmentioning

confidence: 99%

“…56 Preparation of multiple polymers is generally performed using polymerisation methods such as suspension, emulsion, bulk and interfacial polymerisation. 55 This position has, however, been contested by Li, 54 indicating that the polymerisation process can only be classified under two systems, depending on the medium and the phases that exist. Due to this assertion, it has been clarified that polymerisation systems are mostly heterogeneous (ie, they involve more than one phase for the monomer, polymer and initiator), for example, suspension polymerisation, emulsion polymerisation, solid-phase polymerisation and gas-phase polymerisation, or homogeneous (ie, involving only one phase for all the chemicals), for example, solution and bulk polymerisation.…”

Section: Polymerisationmentioning

confidence: 99%

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An overview of the science and art of encapsulated pigments: Preparation, performance and application

Tawiah

Asinyo

Frimpong

et al. 2022

Coloration Technology

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Pigments are classified as organic or inorganic based on their chemical composition. 1,2 Typically, organic pigments comprise compounds of carbon elements that participate in covalent bonding, while inorganic pigments consist primarily of ground minerals such as metals, metallic salts (except barium salts of dyes) and metalloid salts, which do not contain carbon bonds. 3 Although some organic pigments may contain inorganic elements as stabilisers, organic pigments are defined primarily based on their congugated carbon bonds (except carbon black). 2 To improve the chemical, thermal, freeze-thaw and dispersion stability of organic pigments upon application, these classes of pigments have been the subject of extensive research over the years due to their obvious advantages. [4][5][6] Typically, the colour strength and optical properties of coated/printed substrates depend largely on the quality of the pigmented ink/paste and the nature of the substrate. The quality of the pigmented ink/paste then rests on the quality of the dispersion system (ie, the degree of the dispersion and its stability). 5,7 Dispersion stability is very important from the point of view of surface coatings and printing systems, especially for encapsulated inks that

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Section: Methods Of Encapsulationmentioning

confidence: 99%

Section: Polymerisationmentioning

confidence: 99%

An overview of the science and art of encapsulated pigments: Preparation, performance and application

Tawiah

Asinyo

Frimpong

et al. 2022

Coloration Technology

View full text Add to dashboard Cite

show abstract

“…Also, monomers can be prepared or fragmented to convert the obtained polymer into a microsphere [ 193 ]. The polymerization process occurs at lower temperatures, and the polymerization of suspension is similar to bulk polymerization [ 194 ].…”

Section: Polymerizationmentioning

confidence: 99%

Bioactive Graphene Quantum Dots Based Polymer Composite for Biomedical Applications

et al. 2022

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Today, nanomedicine seeks to develop new polymer composites to overcome current problems in diagnosing and treating common diseases, especially cancer. To achieve this goal, research on polymer composites has expanded so that, in recent years, interdisciplinary collaborations between scientists have been expanding day by day. The synthesis and applications of bioactive GQD-based polymer composites have been investigated in medicine and biomedicine. Bioactive GQD-based polymer composites have a special role as drug delivery carriers. Bioactive GQDs are one of the newcomers to the list of carbon-based nanomaterials. In addition, the antibacterial and anti-diabetic potentials of bioactive GQDs are already known. Due to their highly specific surface properties, π-π aggregation, and hydrophobic interactions, bioactive GQD-based polymer composites have a high drug loading capacity, and, in case of proper correction, can be used as an excellent option for the release of anticancer drugs, gene carriers, biosensors, bioimaging, antibacterial applications, cell culture, and tissue engineering. In this paper, we summarize recent advances in using bioactive GQD-based polymer composites in drug delivery, gene delivery, thermal therapy, thermodynamic therapy, bioimaging, tissue engineering, bioactive GQD synthesis, and GQD green resuscitation, in addition to examining GQD-based polymer composites.

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“…One of the major challenges that scientists have sought over the years to overcome and break their restrictions is the response of the organism to drugs, which is one of the types of general responses to the various stressors and environmental impacts in a constantly changing environment Vizirianakis(2014). Thus, for decades the attention and direction was prominent for pharmaceutical research is to modify drug delivery systems and to seek the development of new dosage forms to overcome drug inefficacy and poisoning that lead to the failure of pharmacological treatment through the development of nanoparticle delivery systems as it contributes to providing the required therapeutic amount of medication to the appropriate location In the body to release it immediately and then maintain its desired concentration Negut et al(2017;Thassu Deepak et al(2007). In the first place the main objective of the study is to attracted the attention of interested researchers in this wonderful branch of nanotechnology which known as drug delivery system by examining drug release from different types of nanoparticles based-solid lipid as drug delivery system devices such as matrix system and reservoir devices controlled by the diffusion mechanism and then determin the release profiles for the best device type that is optimal to use as a drug delivery system to cancer cells.…”

Section: Introductionmentioning

confidence: 99%

Utilization of Solid Lipid Nanoparticles Loaded Anticancer Agents as Drug Delivery Systems for Controlled Release

Yahya¹,

Atif²,

Ahmed³

et al. 2019

IJEAST

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Cancer" is the most terrifying disease, just hearing the word "C" is a horror for every patient. Notably, the conventional doses form of taking the anticancer drugs are having ruthless side effects and high toxicity on the patient's body. The design of nanoparticles while maintaining the sink condition in the laboratory release trials is one of the biggest challenges and difficulties in design, especially those low-solubility drugs that are used as anticancer agent carriers. If the doctor is aware of the pharmacokinetics of chemotherapy, it will facilitate and help in determining the amount of dosage required in order to obtain a high therapeutic accuracy and reduce toxicity and affect healthy cells. For this purpose, this paper aims to simulate the pharmacokinetic of different types of chemotherapeutic agents to study the kinetics based on solid lipid drug delivery systems nanoparticles (SLN) by examining drug release from different types of devices such as matrix system and reservoir devices controlled by the diffusion mechanism using preposed and estimated values extracted from literature studies which will help to manufacture nanoparticles that meet specific requirements. In order to determine which device type is optimal and best to use as a drug delivery system to cancerous cells and then examin the effect of particle size of this type, ranging from 10 to 100 nm on the anticancer drug relese and decide the best size that give the requierd dose of each chemotherapy drugs that were used in this study, we simulated the release behavior of nanoparticles with nano-sphare geometry using the MATLAB software. As majour finding of this study, the solid lipid based nanoparticles for drug delivery with matrix solution system type shows prolonged drug release which means that this type of systems have high loading capacity of the various chemotheraputic active compounds and can be use sucssfuly as anticancer agent drug delivery.

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Microscale Drug Delivery Systems: Current Perspectives and Novel Approaches

Cited by 4 publications

References 146 publications

An overview of the science and art of encapsulated pigments: Preparation, performance and application

An overview of the science and art of encapsulated pigments: Preparation, performance and application

Bioactive Graphene Quantum Dots Based Polymer Composite for Biomedical Applications

Utilization of Solid Lipid Nanoparticles Loaded Anticancer Agents as Drug Delivery Systems for Controlled Release

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