This paper presents research on the influence of material anisotropy caused by the technological process of its manufacturing on the plastic properties of the material. In the experimental study, samples cut from an AISI 304L rolled sheet in the rolling direction, transverse, and at a 45° angle to the rolling direction were predeformed by axial deformation at 18 and 30%. The principal specimens extracted from the pre-deformed plates, cut in the longitudinal, transverse, and 45° angle directions, were subjected to tensile loading until failure. The data thus obtained allowed for the analysis of the plastic flow mechanism using the author’s calculation procedure. The CR coefficient analysis provided information on the state of plastic anisotropy caused by the pre-deformation. For the specimens predeformed in the rolling direction, plastic flow isotropy was observed at a strain of 35%. For the specimens predeformed in the transverse direction—the plastic anisotropy is completely removed at a strain of 33%. For the specimens predeformed at 45 degrees to the rolling direction, it was found that the strain completely removed the plastic anisotropy induced by rolling. The calculations provided information that due to an abrupt change in the strain path, a strong reconfiguration of the plastic flow mechanism occurs, causing the removal of anisotropy generated by rolling.