Microtubules and the tax payer

Nick, Peter

doi:10.1007/s00709-011-0339-5

Cited by 25 publications

(13 citation statements)

References 112 publications

(107 reference statements)

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“…33 Interestingly, treatment of A. thaliana leaves with DPI that reduces ROS levels alleviates the effects of V. dahliae toxins on the MT cytoskeleton. In addition, Nick 34 noted that biotic stress perception depends on MTs and is also mediated by RBOHC (respiratory burst oxidase homolog), the plant homolog of the NADPH oxidase that upon activation catalyzes ROS production in the apoplast.…”

Section: Imbalanced Ros Levels and Atypical Tubulin Polymer Formationmentioning

confidence: 99%

Plant cell division

Livanos

Apostolakos²,

Galatis³

2012

Plant Signaling & Behavior

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Accumulated evidence indicates that ROS fluctuations play a critical role in cell division. Dividing plant cells rapidly respond to them. Experimental disturbance of ROS homeostasis affects: tubulin polymerization; PPB, mitotic spindle and phragmoplast assembly; nuclear envelope dynamics; chromosome separation and movement; cell plate formation. Dividing cells mainly accumulate at prophase and delay in passing through the successive cell division stages. Notably, many dividing root cells of the rhd2 Arabidopsis thaliana mutants, lacking the RHD2/AtRBOHC protein function, displayed aberrations, comparable to those induced by low ROS levels. Some protein molecules, playing key roles in signal transduction networks inducing ROS production, participate in cell division. NADPH oxidases and their regulators PLD, PI3K and ROP-GTPases, are involved in MT polymerization and organization. Cellular ROS oscillations function as messages rapidly transmitted through MAPK pathways inducing MAP activation, thus affecting MT dynamics and organization. RNS implication in cell division is also considered.

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Section: Imbalanced Ros Levels and Atypical Tubulin Polymer Formationmentioning

confidence: 99%

Plant cell division

Livanos

Apostolakos²,

Galatis³

2012

Plant Signaling & Behavior

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“…Several authors have suggested that gravitropic bending can trigger altered MT organization (Ikushima and Shimmen, 2005; Jacques et al, 2013; Toyota and Gilroy, 2013). In addition, gravitropism can be inhibited by antimicrotubular drugs or mutations affecting the dynamics of MT (Nick, 2012). On the contrary, tropic bending occurred in roots pretreated with microtubule depolymerizing agents (Bisgrove, 2008).…”

Section: Identification Of Cellular and Molecular Actors In Gravisensmentioning

confidence: 99%

Gravity sensing, a largely misunderstood trigger of plant orientated growth

et al. 2014

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Gravity is a crucial environmental factor regulating plant growth and development. Plants have the ability to sense a change in the direction of gravity, which leads to the re-orientation of their growth direction, so-called gravitropism. In general, plant stems grow upward (negative gravitropism), whereas roots grow downward (positive gravitropism). Models describing the gravitropic response following the tilting of plants are presented and highlight that gravitropic curvature involves both gravisensing and mechanosensing, thus allowing to revisit experimental data. We also discuss the challenge to set up experimental designs for discriminating between gravisensing and mechanosensing. We then present the cellular events and the molecular actors known to be specifically involved in gravity sensing.

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“…). Besides, diverse types of stress induce reorganization of the microtubule (MT) cytoskeleton, thus MTs are nowadays considered as emerging components of plant sensory mechanisms (Nick ).…”

Section: Introductionmentioning

confidence: 99%

Phosphorylation of a p38‐like MAPK is involved in sensing cellular redox state and drives atypical tubulin polymer assembly in angiosperms

Livanos

Galatis

Gaitanaki

et al. 2013

Plant Cell & Environment

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Reactive oxygen species (ROS) imbalance is a stressful condition for plant cells accompanied by dramatic changes in tubulin cytoskeleton. Here, evidence is provided that alterations in ROS levels directly interfere with the phosphorylation state of a p38-like MAPK in the angiosperms Triticum turgidum and Arabidopsis thaliana. Both oxidative stress generators and chemicals inducing ROS scavenging or decreasing ROS production resulted in the accumulation of a phospho-p46 protein similar to p38-MAPK. Importantly, the rhd2 A. thaliana mutants exhibited a remarkable increase in levels of phospho-p46. The presence of the p38-MAPK inhibitor SB203580 attenuated the response to ROS disturbance, prevented microtubule disappearance and resulted in a dramatic decrease in the number of atypical tubulin polymers. Moreover, in roots treated simultaneously with substances inducing ROS overproduction and others resulting in low ROS levels, phospho-p46 levels and the organization of tubulin cytoskeleton were similar to controls. Collectively, our experimental data suggest, for the first time in plants, that p46 functions as a putative sensor of redox state, the activation of which initiates downstream signalling events leading to microtubule disruption and subsequent assembly of atypical tubulin polymers. Thus, p46 seems to participate in perception of ROS homeostasis disturbance as well as in cellular responses to redox imbalance.

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Microtubules and the tax payer

Cited by 25 publications

References 112 publications

Plant cell division

Plant cell division

Gravity sensing, a largely misunderstood trigger of plant orientated growth

Phosphorylation of a p38‐like MAPK is involved in sensing cellular redox state and drives atypical tubulin polymer assembly in angiosperms

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