Microvascular Imaging Using Swept-Source Optical Coherence Tomography with Single-Channel Acquisition

Abstract

This study proposes a new approach to improve the phase stability for swept-source optical coherence tomography (SS-OCT) with single-channel acquisition. This approach can improve the phase instability due to the A-scan trigger jitter from the swept source, or the asynchronization between the A-scan trigger and high-speed digitizer, which enables the visualization of vascular structures by SS-OCT. Aside from reducing the phase noise of the OCT system, only one channel is required for the A-scan trigger, data storage, and wavelength calibration by implementing the proposed approach. Finally, human skin was scanned in vivo to demonstrate the vascular images.

Split-spectrum amplitude-decorrelation angiography with optical coherence tomography

“…Compared with spectral OCT, swept-source OCT introduces another source of phase variation from the cycle-to-cycle tuning and timing variabilities [29]. This makes phase-based angiography noisier.…”

Optical Microangiography Based on Optical Coherence Tomography

“…As a result the axial velocity is small which yields a low-signal-to-noise ratio on the phase data. In other cases, there is low phase stability in the OCT system, such as in the application of several swept source OCT systems, where a source of phase noise is introduced from the cycle-to-cycle tuning and timing variability [29]. For these cases, the use of the phase information is highly susceptible to error.…”

Evaluation of Moisture-Related Attenuation Coefficient and Water Diffusion Velocity in Human Skin Using Optical Coherence Tomography

“…Figure 1(a) shows a schematic diagram of the portable SS-OCT system used for studying water diffusion in the skin [38]. The central wavelength and the scanning range of the swept source are 1,310 nm and 110 nm, respectively.…”