2008
DOI: 10.1107/s0909049507061468
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Migration of mercury from dental amalgam through human teeth

Abstract: Exposure to mercury from dental amalgams, with possible negative health effects, has generally been considered to occur via either erosion or evaporation directly from the surface of fillings, followed by ingestion. The aim of this study was to determine the relative importance of the direct migration of mercury through the tooth as an alternative exposure pathway. X-ray fluorescence imaging has been used to determine quantitatively the spatial distribution of Hg, Ca, Zn and Cu in sections of human teeth that … Show more

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Cited by 37 publications
(51 citation statements)
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“…The idea that other metals such as Zn and the above contained in the amalgam could also diffuse during the drilling process is also chemically unrealistic, especially since some of these were substantially incorporated into the hydroxyapatite, as well as the tubules, many millimetres from the drilling site in the teeth that we analyzed. Thus the unpublished results reported in the comment provide support for our analytical procedures in that their results are entirely consistent with our results (Harris et al, 2008b) where Fig. 3 of this reference shows that a maximum Cu hotspot concentration of 4 mg g À1 was reported in areas where there was no dental amalgam.…”
supporting
confidence: 81%
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“…The idea that other metals such as Zn and the above contained in the amalgam could also diffuse during the drilling process is also chemically unrealistic, especially since some of these were substantially incorporated into the hydroxyapatite, as well as the tubules, many millimetres from the drilling site in the teeth that we analyzed. Thus the unpublished results reported in the comment provide support for our analytical procedures in that their results are entirely consistent with our results (Harris et al, 2008b) where Fig. 3 of this reference shows that a maximum Cu hotspot concentration of 4 mg g À1 was reported in areas where there was no dental amalgam.…”
supporting
confidence: 81%
“…3 of this reference shows that a maximum Cu hotspot concentration of 4 mg g À1 was reported in areas where there was no dental amalgam. The average concentrations over the discoloured areas (results to be published) were similar to those reported in the comment by Guzzi & Pigatto. Moreover, as reported in our paper (Harris et al, 2008b), the X-ray fluorescence also determines the concentration of other elements, such as Ag (see Fig. 4 of Harris et al, 2008b), and these metals in the area of discolouration are consistent with those in bulk dentine found by them.…”
supporting
confidence: 60%
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