Milk Other than Breast Milk and the Development of Asthma in Children 3 Years of Age. A Birth Cohort Study (2006-2011)

Allergic diseases are becoming a major healthcare issue in many developed nations, where living environment and lifestyle are most predominantly distinct. Such differences include urbanized, industrialized living environments, overused hygiene products, antibiotics, stationary lifestyle, and fast-food-based diets, which tend to reduce microbial diversity and lead to impaired immune protection, which further increase the development of allergic diseases. At the same time, studies have also shown that modulating a microbiocidal community can ameliorate allergic symptoms. Therefore, in this paper, we aimed to review recent findings on the potential role of human microbiota in the gastrointestinal tract, surface of skin, and respiratory tract in the development of allergic diseases. Furthermore, we addressed a potential therapeutic or even preventive strategy for such allergic diseases by modulating human microbial composition.

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Diet Modifications in Primary Prevention of Asthma. Where Do We Stand?

Sozańska

Sikorska-Szaflik

2021

Nutrients

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The steep increase in asthma prevalence, observed worldwide in recent decades, has created an urgent need to search for effective methods of its prevention. Among other environmental factors, changes in diet habits and the potential influence of individual food components on immunological processes have been extensively studied as a potential method of intervention in primary prevention of asthma. The preventive role of some nutrients has been confirmed: unpasteurized milk reduced the risk of asthma in epidemiological studies, vitamin D supplementation was effective in preventing the transient forms of wheezing in small children and high maternal intake of fish oil reduced the risk of persistent wheeze and asthma in children. However, not all studies provided consistent results, and many food ingredients are still pending for defining their role in asthma development. Moreover, a novel approach looking not only at single food ingredients, but the whole dietary patterns and diversity has recently been proposed. In this paper, we discuss the current role of nutrients in asthma primary prevention and the reasons for inconsistencies in the study results. We look at single diet components, but also the whole dietary patterns. We describe the proposed mechanisms of action at different stages of life, identify the role of modifiers and delineate future perspectives on the application of nutrients in targeting strategies for asthma primary prevention.

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Milk Other than Breast Milk and the Development of Asthma in Children 3 Years of Age. A Birth Cohort Study (2006-2011)

Abstract: Prevalence of asthma in Australian children is amongst the highest in the world.

Cited by 4 publications

References 54 publications

Mother-to-Child Signaling through Breast Milk Biomolecules

Mother-to-Child Signaling through Breast Milk Biomolecules

The Role of Early Life Microbiota Composition in the Development of Allergic Diseases

Diet Modifications in Primary Prevention of Asthma. Where Do We Stand?

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