Millimeter-Wave-Based Spoof Localized Surface Plasmonic Resonator for Sensing Glucose Concentration

Kim, Yelim; Salim, Ahmed; Lim, Sungjoon

doi:10.3390/bios11100358

Cited by 15 publications

(6 citation statements)

References 43 publications

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“…Microwave resonators not only are used for communication systems [39][40][41][42][43][44] , but they are also used as sensors for multiple applications [45][46][47][48] . Compared to the conventional microwave resonators, Surface plasmonic resonators are reported as highly sensitive resonators by which the EM waves can strongly interact with the surrounding medium [49][50][51] .…”

Section: Microwave Plasmonic Fano Resonance Sensormentioning

confidence: 99%

On-body non-invasive glucose monitoring sensor based on high figure of merit (FoM) surface plasmonic microwave resonator

Soltanian,

Nosrati,

Mobayen

et al. 2023

Sci Rep

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High-figure of merit (FoM) plasmonic microwave resonator is researched as a non-invasive on-body sensor to monitor the human body's blood glucose variation rate in adults for biomedical applications, e.g., diabetic patients. The resonance frequencies of the proposed sensor are measured to be around $${f}_{01}=3.25$$ f 01 = 3.25 GHz and $${f}_{01}=4.67$$ f 01 = 4.67 GHz over the frequency band of DC to 6GHz which are suitable for monitoring interstitial fluid (ISF) changing rate. The $$40\times 40 {\mathrm{mm}}^{2}$$ 40 × 40 mm 2 sensor is experimentally wrapped on the human body arm to monitor the blood glucose changing rate via amplitude and frequency variations of the sensor. Amplitude variation and frequency shift are measured to be around 7 dB and 30 MHz, respectively. The measured results demonstrate the high precision of the proposed approach to depict a valid diagram for glucose changing rate due to good impedance matching of the designed microwave sensor and human body. The sensor is shown to enhance the sensitivity by a factor of 5 compared to the conventional ones.

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Section: Microwave Plasmonic Fano Resonance Sensormentioning

confidence: 99%

On-body non-invasive glucose monitoring sensor based on high figure of merit (FoM) surface plasmonic microwave resonator

Soltanian,

Nosrati,

Mobayen

et al. 2023

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Among the broad application scenarios, biomedical applications based on the microwave resonance sensors attract the most attention, such as glucose concentration sensing, [8,9,21,22] antigen-antibody analysis, [23,24] single-cell detection, [25] etc. These sensing signals originate from the permittivity changes of the solutions under test, which are caused by the concentration variations of the target biomedical quantities.…”

Section: Introductionmentioning

confidence: 99%

Impacts of Liquid Level on Microwave Resonance Sensing with a Flexible Microfluidic Channel

Wang

Zhang

et al. 2023

Advanced Sensor Research

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Permittivity sensing based on resonance tracking lays the fundamental principle for a variety of biochemical sensors, which has found vast applications in cancer biomarker detection, antigen-antibody analysis, and so on. Driven by continuous promotion of the detection limit, precise environmental control highlights its critical importance. Here, the impacts of liquid level on microwave resonance sensing are investigated, in which a flexible polydimethylsiloxane microfluidic channel and soft tubing are employed to control the liquid under test. The hydraulic pressure affects the effective permittivity of the liquid and the channel material, hence causing extra resonance shift signals. Both contactless and contacting sensing scenarios are studied in numerical simulations and experiments. It is demonstrated that the resonance frequency varies sensitively with the liquid level, and a sensitivity of 343 kHz mm −1 is measured. Meanwhile, a spoof localized surface plasmon resonator and its optimized excitation structure are employed and analyzed for a good figure of merit, addressing the detectability difficulties for high-permittivity and high-loss aqueous solutions. These results provide general guidelines for understanding and controlling the resonance sensors in aqueous environments and help to realize further lower detection limits.

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“…Terahertz spectroscopy is an important means for investigating the characteristics of biomolecules, such as carbohydrates, proteins, and DNA [ 1 , 2 , 3 , 4 , 5 , 6 ], as their vibration and rotation frequencies fall within the terahertz frequency range, allowing them to exhibit certain absorption properties in this band [ 6 , 7 , 8 , 9 ]. Despite the potential of terahertz waves to measure biomolecules, their limited interaction makes it difficult to achieve high sensitivity detection of target biomolecules and distinguish multiple biomolecules [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Exploring the Application of Multi-Resonant Bands Terahertz Metamaterials in the Field of Carbohydrate Films Sensing

Zhang

Guo

et al. 2023

Biosensors

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Terahertz spectroscopy is a powerful tool for investigating the properties and states of biological matter. Here, a systematic investigation of the interaction of THz wave with “bright mode” resonators and “dark mode” resonators has been conducted, and a simple general principle of obtaining multiple resonant bands has been developed. By manipulating the number and positions of bright mode and dark mode resonant elements in metamaterials, we realized multi-resonant bands terahertz metamaterial structures with three electromagnetic-induced transparency in four-frequency bands. Different carbohydrates in the state of dried films were selected for detection, and the results showed that the multi-resonant bands metamaterial have high response sensitivity at the resonance frequency similar to the characteristic frequency of the biomolecule. Furthermore, by increasing the biomolecule mass in a specific frequency band, the frequency shift in glucose was found to be larger than that of maltose. The frequency shift in glucose in the fourth frequency band is larger than that of the second band, whereas maltose exhibits an opposing trend, thus enabling recognition of maltose and glucose. Our findings provide new insights into the design of functional multi-resonant bands metamaterials, as well as new strategies for developing multi-band metamaterial biosensing devices.

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Millimeter-Wave-Based Spoof Localized Surface Plasmonic Resonator for Sensing Glucose Concentration

Cited by 15 publications

References 43 publications

On-body non-invasive glucose monitoring sensor based on high figure of merit (FoM) surface plasmonic microwave resonator

On-body non-invasive glucose monitoring sensor based on high figure of merit (FoM) surface plasmonic microwave resonator

Impacts of Liquid Level on Microwave Resonance Sensing with a Flexible Microfluidic Channel

Exploring the Application of Multi-Resonant Bands Terahertz Metamaterials in the Field of Carbohydrate Films Sensing

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